ArticleThe Journal of biological chemistry2016
Cyclable Condensation and Hierarchical Assembly of Metastable Reflectin Proteins, the Drivers of Tunable Biophotonics.
Article in The Journal of biological chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Cephalopod proteins for bioinspired and sustainable biomaterials design.Materials today. Bio · 2025Review
- Neural responses to light stimulation in the octopus arm.The Journal of experimental biology · 2025Article
- Electrochemically Driven Optical Dynamics of Reflectin Protein Films.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- A colloidal model for the equilibrium assembly and liquid-liquid phase separation of the reflectin A1 protein.Biophysical journal · 2024Article
- Reversible and size-controlled assembly of reflectin proteins using a charged azobenzene photoswitch.Chemical science · 2024Article
- Protein Charge Neutralization Is the Proximate Driver Dynamically Tuning Reflectin Assembly.International journal of molecular sciences · 2024Article
- Voltage-calibrated, finely tunable protein assembly.Journal of the Royal Society, Interface · 2023Article
- A new electrochemical method that mimics phosphorylation of the core tau peptide K18 enables kinetic and structural analysis of intermediates and assembly.The Journal of biological chemistry · 2023Article
- Synthetic peptides for the precise transportation of proteins of interests to selectable subcellular areas.Frontiers in bioengineering and biotechnology · 2023Article
- A Mini-Review on Reflectins, from Biochemical Properties to Bio-Inspired Applications.International journal of molecular sciences · 2022Review
- At the Intersection of Natural Structural Coloration and Bioengineering.Biomimetics (Basel, Switzerland) · 2022Review
- Tunable Cellular Localization and Extensive Cytoskeleton-Interplay of Reflectins.Frontiers in cell and developmental biology · 2022Article
- Seeing Keratinocyte Proteins through the Looking Glass of Intrinsic Disorder.International journal of molecular sciences · 2021Review
- Design and fabrication of recombinant reflectin-based multilayer reflectors: bio-design engineering and photoisomerism induced wavelength modulation.Scientific reports · 2021Article
- Structure, self-assembly, and properties of a truncated reflectin variant.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Electrochemistry as a surrogate for protein phosphorylation: voltage-controlled assembly of reflectin A1.Journal of the Royal Society, Interface · 2020Article
- Recent advances in bioelectronics chemistry.Chemical Society reviews · 2020Review
- Cephalopod-inspired optical engineering of human cells.Nature communications · 2020Article
- Calibration between trigger and color: Neutralization of a genetically encoded coulombic switch and dynamic arrest precisely tune reflectin assembly.The Journal of biological chemistry · 2019Article
- Synthetic biology for fibres, adhesives and active camouflage materials in protection and aerospace.MRS communications · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reversible changes in the phosphorylation of reflectin proteins have been shown to drive the tunability of color and brightness of light reflected from specialized cells in the skin of squids and related cephalopods. We show here, using dynamic light scattering, electron microscopy, and fluorescence analyses, that reversible titration of the excess positive charges of the reflectins, comparable with that produced by phosphorylation, is sufficient to drive the reversible condensation and hierarchical assembly of these proteins. The results suggest a two-stage process in which charge neutralization first triggers condensation, resulting in the emergence of previously cryptic structures that subsequently mediate reversible, hierarchical assembly. The extent to which cyclability is seen in the in vitro formation and disassembly of complexes estimated to contain several thousand reflectin molecules suggests that intrinsic sequence- and structure-determined specificity governs the reversible condensation and assembly of the reflectins and that these processes are therefore sufficient to produce the reversible changes in refractive index, thickness, and spacing of the reflectin-containing subcellular Bragg lamellae to change the brightness and color of reflected light. This molecular mechanism points to the metastability of reflectins as the centrally important design principle governing biophotonic tunability in this system.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.