Evidence map›Paper›PMID 26718928›Full record

ArticleJournal of cardiovascular translational research2016

Standard Operating Procedures (SOPs) for Evaluating the Heart in Preclinical Studies of Duchenne Muscular Dystrophy.

Dongsheng Duan, Jill A Rafael-Fortney, Alison Blain, David A Kass, Elizabeth M McNally, Joseph M Metzger, Christopher F Spurney, Kathi Kinnett

Abstract readLetter
In one paragraph

Article in Journal of cardiovascular translational research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dongsheng DuanDepartment of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO, USA.
Jill A Rafael-FortneyDepartments of Physiology & Cell Biology and Molecular & Cellular Biochemistry, College of Medicine, The Ohio State University, Columbus, OH, USA.
Alison BlainInstitute of Genetic Medicine, Newcastle University, Newcastle, UK.
David A KassThe Johns Hopkins University Medical Institutions, Baltimore, MD, USA.
Elizabeth M McNallyCenter for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Joseph M MetzgerDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN, USA.
Christopher F SpurneyDivision of Cardiology and Center for Genetic Medicine Research, Children's National Heart Institute, Children's National Health System, Washington, DC, USA.
Kathi KinnettParent Project Muscular Dystrophy, Middletown, OH, USA. kathi@parentprojectmd.org.

Funding

Training and education CoreU54AR052646 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MCNALLY, ELIZABETH M, SWEENEY, H LEE · 2005 to 2020
$24.1M
SARCOGLYCAN IN MYOPATHY AND MUSCLE MEMBRANE STABILITYR01HL061322 · NHLBI · UNIVERSITY OF CHICAGO · PI MCNALLY, ELIZABETH M · 1999 to 2022
$7.5M
Regulation of TGF - (beta) pathways in muscular dystrophy fibrosisP01NS072027 · NINDS · UNIVERSITY OF CHICAGO · PI MCNALLY, ELIZABETH M · 2011 to 2015
$6.2M
Targeted membrane integrity in cardiac ischemia and reperfusionR01HL122323 · NHLBI · UNIVERSITY OF MINNESOTA · PI METZGER, JOSEPH MARK · 2015 to 2022
$5.1M
NHLBI NIH HHS R01 HL061322NHLBI NIH HHS R01 HL122323NIAMS NIH HHS U54 AR052646NINDS NIH HHS P01 NS072027
6 · The paper itself

Abstract

A recent working group meeting focused on contemporary cardiac issues in Duchenne muscular dystrophy (DMD) was hosted by the National Heart, Lung, and Blood Institute in collaboration with the Parent Project Muscular Dystrophy. An outcome of this meeting was to provide freely available detailed protocols for preclinical animal studies. The goal of these protocols is to improve the quality and reproducibility of cardiac preclinical studies aimed at developing new therapeutics for the prevention and treatment of DMD cardiomyopathy.

Indexed as

Biomedical ResearchHeartMuscular Dystrophy, DuchenneMyocardiumAnimalsConsensusConsensus Statements as TopicDisease Models, AnimalPractice Guidelines as TopicReproducibility of ResultsCardiologyCardiomyopathyDuchennePreclinicalStandard operating procedures (SOPs)

Identifiers

PMID26718928
PMCPMC5509361

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.