Evidence map›Paper›PMID 26718859›Full record

ArticleThe Annals of thoracic surgery2016

Clinical Characteristics and Outcomes of Patients With Myocardial Infarction and Cardiogenic Shock Undergoing Coronary Artery Bypass Surgery: Data From The Society of Thoracic Surgeons National Database.

Deepak Acharya, Brian C Gulack, Renzo Y Loyaga-Rendon, James E Davies, Xia He, J Matthew Brennan, Vinod H Thourani, Matthew L Williams

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in The Annals of thoracic surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
  2. Article
  3. The History of Coronary Artery Disease.The International journal of angiology : official publication of the International College of Angiology, Inc · 2025
    Review
  4. Article
  5. Article
  6. The role of temporary mechanical circulatory support in heart failure.European heart journal supplements : journal of the European Society of Cardiology · 2025
    Article
  7. Emergent coronary revascularization with percutaneous coronary intervention and coronary artery bypass grafting in patients receiving extracorporeal cardiopulmonary resuscitation.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2024
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Ventricular Unloading Using the ImpellaFrontiers in cardiovascular medicine · 2022
    Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Mechanical support for high-risk coronary artery bypass grafting.Indian journal of thoracic and cardiovascular surgery · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Deepak AcharyaDivision of Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: dacharya@uab.edu.
Brian C GulackDepartment of General Surgery, Duke University, Durham, North Carolina.
Renzo Y Loyaga-RendonDivision of Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, Alabama.
James E DaviesDivision of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Alabama.
Xia HeDuke Clinical Research Institute, Durham, North Carolina.
J Matthew BrennanDivision of Cardiology, Duke University, Durham, North Carolina.
Vinod H ThouraniDivision of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, Georgia.
Matthew L WilliamsDivision of Cardiothoracic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.
University of Alabama at Birmingham · USDuke University · USClinical Research Institute · USEmory University · USUniversity of Pennsylvania · US

Funding

Cardiothoracic Surgical Network Clinical CenterU01HL088953 · NHLBI · DUKE UNIVERSITY · PI SMITH, PETER K · 2007 to 2013
$2.6M
Core Clinical Centers for the CTSNUM1HL088953 · NHLBI · DUKE UNIVERSITY · PI SMITH, PETER K · 2013 to 2017
$2.5M
NHLBI NIH HHS U01 HL088953NHLBI NIH HHS UM1 HL088953
6 · The paper itself

Abstract

backgroundAcute myocardial infarction complicated by cardiogenic shock (AMI-CS) is associated with substantial mortality. We evaluated outcomes of patients in The Society of Thoracic Surgeons Adult Cardiac Surgery Database who underwent coronary artery bypass graft surgery (CABG) in the setting of AMI-CS.

methodsAll patients with AMI-CS who underwent nonelective CABG or CABG with ventricular assist device implantation within 7 days after myocardial infarction were enrolled. The primary analysis sample consisted of patients who underwent surgery between June 2011 and December 2013. Baseline characteristics, operative findings, outcomes, and the utilization of mechanical circulatory support (MCS) were assessed in detail in this population. We also evaluated trends in unadjusted mortality for all patients undergoing CABG or CABG with ventricular assist device for AMI-CS from January 2005 to December 2013.

resultsA total of 5,496 patients met study criteria, comprising 1.5% of all patients undergoing CABG during the study period. Overall operative mortality was 18.7%, decreasing from 19.3% in 2005 to 18.1% in 2013 (p < 0.001). Use of MCS increased from 5.8% in 2011 to 8.8% in 2013 (p = 0.008). Patients receiving MCS had a high proportion of cardiovascular risk factors or high clinical acuity. Patients requiring preoperative and patients requiring intraoperative or postoperative MCS had operative mortality of 37.2% and 58.4%, respectively. Patients undergoing CABG as a salvage procedure had an operative mortality of 53.3%, and a high incidence of reoperation (21.8%), postoperative respiratory failure requiring prolonged ventilation (59.7%), and renal failure (18.5%).

conclusionsMost patients undergoing CABG for AMI-CS have a sizeable but not prohibitive risk. Patients who require MCS and those undergoing operation as a salvage procedure reflect higher risk populations.

Indexed as

Heart-Assist DevicesRegistriesSocieties, MedicalThoracic SurgeryAgedCoronary Artery BypassFemaleHumansMaleMiddle AgedMyocardial InfarctionRetrospective StudiesRisk FactorsShock, CardiogenicSurvival RateUnited States

Identifiers

PMID26718859
PMCPMC5142520
OpenAlexW2217222360

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.