Evidence map›Paper›PMID 26718268›Full record

ArticleHealth and quality of life outcomes2015

Depression with pain co morbidity effect on quality of life among HIV positive patients in Uganda: a cross sectional study.

Emmanuel K Mwesiga, Levi Mugenyi, Noeline Nakasujja, Shirley Moore, Mark Kaddumukasa, Martha Sajatovic

Open access · goldAbstract read
In one paragraph

Article in Health and quality of life outcomes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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  13. Socioeconomic Vulnerability to Depressive Symptoms in Patients with Chronic Hepatitis B.International journal of environmental research and public health · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Emmanuel K MwesigaCollege of Health Sciences, Makerere University, 7072, Kampala, Uganda. emwesiga@chs.mak.ac.ug.
Levi MugenyiInfectious Disease Research Collaboration, Mulago Hill Road, MUJHU3 Building, P.O. Box 7475, Kampala, Uganda.
Noeline NakasujjaCollege of Health Sciences, Makerere University, 7072, Kampala, Uganda.
Shirley MooreNeurological and Behavioral Outcomes Center, University Hospital Case Medical Center, Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH, 44106, USA.
Mark KaddumukasaCollege of Health Sciences, Makerere University, 7072, Kampala, Uganda.
Martha SajatovicNeurological and Behavioral Outcomes Center, University Hospital Case Medical Center, Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH, 44106, USA.
Makerere University · UGCase Western Reserve University · USInfectious Diseases Research Collaboration · UG

Funding

Research & training:improve quality of care for neurological disorders in UgandaR25NS080968 · NINDS · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI KATABIRA, ELLY T · 2012 to 2014
$792k
NINDS NIH HHS R25 NS080968NINDS NIH HHS R25NS080968
6 · The paper itself

Abstract

backgroundDepression with pain comorbidity (DPC) has not been clearly defined among HIV positive patients in sub-Saharan Africa. It still remains a challenge despite many studies in Africa documenting a high prevalence of pain and depression among people living with HIV/AIDS. Both are associated with a grave impact on the health related outcomes in this pandemic. This study aimed at determining the prevalence, factors associated and effect on quality of life of DPC among HIV positive patients.

methodsIn a cross-sectional survey, 345 HIV positive patients were enrolled into the study. Using a pre-tested standardised questionnaire the presence of DPC was assessed after a written informed consent. The associations between DPC, quality of life, depression history, severity, and cognition were determined. A p-value of <0.05 was considered to be significant.

resultsAmong people living with HIV/AIDS (PLWHA), the prevalence of DPC was about 5%. PLWHA with DPC were more likely to perceive their overall quality of life as poor and scored poorly in all the domains on the WHOQOL-BREF. They were also more likely to have more severe forms of depression and recurrent episodes of depression.

conclusionsDPC is common, under diagnosed and undertreated in PLWHA in Uganda. Depression and pain screening as well as appropriate access to care for DPC have potential to improve quality of life and health outcomes. This calls for the integration and training of mental health services into HIV/AIDS care and future efforts by policy makers and HIV caregivers to address this treatment gap to advance the care of people living with HIV in Uganda.

Indexed as

Quality of LifeAdultAfrica South of the SaharaChronic PainComorbidityCross-Sectional StudiesDepressionFemaleHIV InfectionsHumansMaleMiddle AgedPain ManagementPrevalenceSocioeconomic FactorsUganda

Identifiers

PMID26718268
PMCPMC4697332
OpenAlexW2202313463

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.