SynthesisMedicine2015
Comparison of Diagnostic Accuracy of Real-Time Elastography and Shear Wave Elastography in Differentiation Malignant From Benign Thyroid Nodules.
Synthesis in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Diagnostic and clinical utility of ultrasound elastography for uterine cervical neoplasms-a comprehensive systematic review and meta-analysis.Abdominal radiology (New York) · 2026Pooled it
- US-Elastography With Different Techniques for Thyroid Nodule Characterization: Systematic Review and Meta-analysis.Frontiers in oncology · 2022Pooled it
- Article
- Comparative Analysis of Diagnostic Performance Between Elastography and AI-Based S-Detect for Thyroid Nodule Detection.Diagnostics (Basel, Switzerland) · 2025Article
- Adenocarcinoma admixed with neuroendocrine carcinoma of the cervix: A case report and review of literature.Case reports in women's health · 2024Article
- Diagnostic Accuracy of Strain Ultrasound Elastography in Thyroid Lesions Compared to Fine-Needle Aspiration Cytology.Cureus · 2022Article
- Diagnostic performance of C-TIRADS combined with SWE for the diagnosis of thyroid nodules.Frontiers in endocrinology · 2022Article
- Evaluation of thyroid nodules by shear wave elastography: a review of current knowledge.Journal of endocrinological investigation · 2021Review
- TIRADS, SRE and SWE in INDETERMINATE thyroid nodule characterization: Which has better diagnostic performance?La Radiologia medica · 2021Article
- Thyroid Nodule Characterization: How to Assess the Malignancy Risk. Update of the Literature.Diagnostics (Basel, Switzerland) · 2021Review
- Web-Based Ultrasonic Nomogram Predicts Preoperative Central Lymph Node Metastasis of cN0 Papillary Thyroid Microcarcinoma.Frontiers in endocrinology · 2021Article
- Real-Time Elastography: A Web-Based Nomogram Improves the Preoperative Prediction of Central Lymph Node Metastasis in cN0 PTC.Frontiers in oncology · 2021Article
- Elastography for the diagnosis of high-suspicion thyroid nodules based on the 2015 American Thyroid Association guidelines: a multicenter study.BMC endocrine disorders · 2020Article
- Ultrasound Real-Time Tissue Elastography Improves the Diagnostic Performance of the ACR Thyroid Imaging Reporting and Data System in Differentiating Malignant from Benign Thyroid Nodules: A Summary of 1525 Thyroid Nodules.International journal of endocrinology · 2020Article
- Role of Strain Elastography and Shear-Wave Elastography in a Multiparametric Clinical Approach to Indeterminate Cytology Thyroid Nodules.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Article
- Sonographic Evaluation of Thyroid Nodules with Elastography and Cytopathological Correlation.Journal of pharmacy & bioallied sciencesArticle
- Comparison of Strain Elastography, Shear Wave Elastography, and Conventional Ultrasound in Diagnosing Thyroid Nodules.Journal of medical ultrasoundArticle
Corrections and comments
- Erratum issued
- Erratum issuedGu, Lingji [Corrected to Guo, Lingji]
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thyroid nodules are relatively more prevalent in iodine-deficiency area, and the incidence increased sharply in the past decade in these areas. Workup of malignant from benign nodules in clinic was the main problem for managing thyroid nodules.An overall search for the articles about the diagnostic performance of real-time elastography (RTE) and shear wave elastography (SWE) before April 2015 in the databases of PubMed, Embase, and Google scholar. The pooled sensitivity, specificity, and summary receiver operating characteristic (SROC) curve were obtained from individual studies with a random-effects model. Subgroup and meta-regression analysis were also performed.Fifty-six studies involved in 2621 malignant nodules and 7380 benign nodules were contained in our meta-analysis. The pooled sensitivity and specificity of RTE was 83.0% and 81.2%, which is higher than SWE (sensitivity: 78.7%, specificity: 80.5%). The areas under the SROC curve of RTE and SWE were 0.885 and 0.842 respectively. RTE had higher diagnostic value for Caucasians than Asians. Stran ratio (SR) assessment had higher diagnostic performance than elasticity score (ES) system. Similarly, it had higher diagnostic value when malignant nodules were more than 50.In summary, the results revealed that RTE had higher diagnostic performance than SWE in differentiating malignant from benign nodules. However, future international multicenter studies in the region of thyroid risk need to further assess the diagnostic performance of RTE.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.