Evidence map›Paper›PMID 26717118›Full record

ArticleBiotechnology and bioengineering2017

Whole-cell biocatalytic and de novo production of alkanes from free fatty acids in Saccharomyces cerevisiae.

Jee Loon Foo, Adelia Vicanatalita Susanto, Jay D Keasling, Susanna Su Jan Leong, Matthew Wook Chang

Open access · hybridAbstract readLetter
In one paragraph

Article in Biotechnology and bioengineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 66 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Microbial engineering to produce fatty alcohols and alkanes.Journal of industrial microbiology & biotechnology · 2021
    Review
  8. The Model SystemLife (Basel, Switzerland) · 2020
    Review
  9. Mechanism-Driven Metabolic Engineering for Bio-Based Production of FreeFrontiers in bioengineering and biotechnology · 2020
    Article
  10. Article
  11. Effect ofFood science & nutrition · 2019
    Article
  12. Review
  13. Article
  14. Engineering the oleaginous yeastBiotechnology for biofuels · 2019
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jee Loon FooDepartment of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Adelia Vicanatalita SusantoDepartment of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Jay D KeaslingJoint BioEnergy Institute, Emeryville, California.
Susanna Su Jan LeongDepartment of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Matthew Wook ChangDepartment of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
National University of Singapore · SGJoint BioEnergy Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid global industrialization in the past decades has led to extensive utilization of fossil fuels, which resulted in pressing environmental problems due to excessive carbon emission. This prompted increasing interest in developing advanced biofuels with higher energy density to substitute fossil fuels and bio-alkane has gained attention as an ideal drop-in fuel candidate. Production of alkanes in bacteria has been widely studied but studies on the utilization of the robust yeast host, Saccharomyces cerevisiae, for alkane biosynthesis have been lacking. In this proof-of-principle study, we present the unprecedented engineering of S. cerevisiae for conversion of free fatty acids to alkanes. A fatty acid α-dioxygenase from Oryza sativa (rice) was expressed in S. cerevisiae to transform C

Indexed as

BiofuelsAlkanesBiocatalysisBioreactorsDioxygenasesFatty Acids, NonesterifiedMetabolic EngineeringOryzaPlant ProteinsRecombinant ProteinsSaccharomyces cerevisiaeAlkanesBiofuelsDioxygenasesFatty Acids, NonesterifiedPlant ProteinsRecombinant Proteinsaldehydealkanebiofuelsde novo biosynthesisfatty acidmetabolic engineeringwhole-cell biocatalysis

Identifiers

PMID26717118
PMCPMC5132040
OpenAlexW2277364219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.