Evidence map›Paper›PMID 26716122›Full record

ArticleEndoscopy international open2015

Is virtual chromoendoscopy useful in the evaluation of subtle ulcerative small-bowel lesions detected by video capsule endoscopy?

Mihai Rimbaş, Lucian Negreanu, Lidia Ciobanu, Andreea Benguş, Cristiano Spada, Cristian Răsvan Băicuş, Guido Costamagna

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Endoscopy international open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Capsule endoscopy of the small bowel.Annals of translational medicine · 2016
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Mihai RimbaşGastroenterology Department, Colentina Clinical Hospital, Bucharest, Romania ; Internal Medicine Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Lucian NegreanuInternal Medicine Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania ; Internal Medicine and Gastroenterology Department, University Emergency Hospital, Bucharest, Romania.
Lidia CiobanuRegional Institute of Gastroenterology and Hepatology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Andreea BenguşInternal Medicine Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Cristiano SpadaDigestive Endoscopy Unit, Università Cattolica del Sacro Cuore, Rome, Italy.
Cristian Răsvan BăicuşInternal Medicine Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania ; Clinical Research Unit RECIF (Réseau d'Epidémiologie Clinique International Francophone), Bucharest, Romania.
Guido CostamagnaDigestive Endoscopy Unit, Università Cattolica del Sacro Cuore, Rome, Italy.
Carol Davila University of Medicine and Pharmacy · ROUniversità Cattolica del Sacro Cuore · ITIuliu Hațieganu University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe identification of subtle small-bowel mucosal lesions by video capsule endoscopy (VCE) can be challenging. Virtual chromoendoscopy techniques, based on narrowing the bandwidth of conventional white light endoscopic imaging (WLI), were developed to improve the analysis of mucosal patterns. However, data on the already-implemented Flexible spectral Imaging (or Fujinon Intelligent) Color Enhancement (FICE) software application in VCE are limited. MATERIALS AND

methodsAn evaluation of 250 difficult-to-interpret small-bowel ulcerative and 50 artifact lesions selected from 64 VCE recordings was conducted by four experienced VCE readers in two steps: initially as WLI, then with the addition of all available virtual chromoendoscopy pre-sets (FICE 1, 2, and 3 and Blue mode). The readers labeled them as real or false ulcerative lesions and rated the usefulness of each of the pre-sets.

resultsBetween the first (WLI-only) and second (virtual chromoendoscopy-aided) readings, in terms of accuracy there was a global 16.5 % (95 % confidence interval [95 %CI] 13.6 - 19.4 %) improvement (P < 0.001), derived from a 22 % [95 %CI 18.9 - 25.1 %] improvement in the evaluation of true ulcerative images (P < 0.001) and an 11 % (95 %CI 4.1 - 17.7 %) decrease in the evaluation of false ulcerative ones (P = 0.003). The FICE 1 and 2 pre-sets were rated as most useful.

conclusionThe application of virtual chromoendoscopy for VCE is useful to better categorize difficult-to-interpret small-bowel mucosal ulcerative lesions. However, care must be taken, and individual images should be evaluated only as part of a sequence in a recording because the technology can also mistakenly guide to the incorrect interpretation of artifacts as ulcerative lesions.

Identifiers

PMID26716122
PMCPMC4683137
OpenAlexW2281329747

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.