ArticleEndoscopy international open2015
A significant feature of microvessels in magnifying narrow-band imaging for diagnosis of early gastric cancer.
Article in Endoscopy international open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Image-Enhanced Endoscopy and Its Corresponding Histopathology in the Stomach.Gut and liver · 2021Review
- Demarcated redness associated with increased vascular density/size: a useful marker of flat-type dysplasia in patients with ulcerative colitis.Endoscopy international open · 2021Article
- Application of linked color imaging in the diagnosis of early gastrointestinal neoplasms and precancerous lesions: a review.Therapeutic advances in gastroenterology · 2021Article
- Clinical applicability of gastroscopy with narrow-band imaging for the diagnosis ofWorld journal of clinical cases · 2020Review
- Risk of multiple early gastric cancers in a patient with precursor lesions and endoscopic surveillance for 7 years: A case report.Medicine · 2019Article
- Utility of linked color imaging for endoscopic diagnosis of early gastric cancer.World journal of gastroenterology · 2019Article
- Multiple convex demarcation line for prediction of benign depressed gastric lesions in magnifying narrow-band imaging.Endoscopy international open · 2018Article
- Immunohistochemical features and staging of early gastric cancer.Archives of medical science : AMS · 2017Article
- Clinical Usefulness of the VS Classification System Using Magnifying Endoscopy with Blue Laser Imaging for Early Gastric Cancer.Gastroenterology research and practice · 2017Article
- Controversies in EUS: Do we need miniprobes?Endoscopic ultrasoundArticle
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND STUDY
aimsMagnifying narrow-band imaging (NBI) is more useful than conventional endoscopy for diagnosing early gastric cancer (EGC). However, evaluation of irregular microvascular patterns is subjective and is often difficult, even with expert eyes. The aim of this study was to clarify the most important microvascular patterns in magnifying NBI for diagnosis of EGC. PATIENTS AND
methodsThis was a post-hoc analysis of a multicenter prospective trial among nine Japanese hospitals. A total of 1353 patients underwent screening with white-light endoscopy and 362 patients had small (≤ 10 mm) depressed lesions. They were randomly assigned to magnifying NBI or white-light endoscopy followed by magnifying NBI. During diagnosis, magnifying NBI images were recorded before biopsy. All magnifying NBI images were reviewed and evaluated for the association of four features of microvessels - that is, dilation, tortuosity, difference in caliber, and variation in shape - with cancer diagnosis.
resultsImages of 343 lesions (40 cancerous and 303 benign depression lesions) were evaluable. The diagnostic performance (sensitivity/specificity) of each finding was: dilation, 25/90 %; tortuosity, 55/24 %; difference in caliber, 13 /99 %; and variation in shape, 70/95 %. Multivariate analysis identified only variation in shape as being statistically significantly associated with diagnosis of cancer (odds ratio 38.0, 95 % confidence interval: 16.1 - 95.7, P < 0.001). All findings showed moderate agreement (κ values): dilation, 0.44; tortuosity, 0.33; difference in caliber, 0.26; and variation in shape, 0.48.
conclusionsA variation in shape was the most significant feature of microvessels observed in magnifying NBI for diagnosis of small depressed-type EGC. STUDY REGISTRATION: UMIN-CTR000001072.
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