Evidence map›Paper›PMID 26716101›Full record

ArticleGerms2015

Antigenic distribution of Streptococcus agalactiae isolates from pregnant women at Garankuwa hospital - South Africa.

Martina O Chukwu, Rooyen Tinago Mavenyengwa, Charles M Monyama, John Y Bolukaoto, Sogolo L Lebelo, Motlatji Rb Maloba, Maphoshane Nchabeleng, Sylvester Rogers Moyo

Abstract read
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In one paragraph

Article in Germs, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Towards a holistic epidemiology ofFrontiers in bioinformatics · 2026
    Article
  2. Distribution and Prevalence of Serotypes of Group BMaternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Molecular Characterization ofJournal of tropical medicine · 2020
    Article
  7. Article
  8. Article
  9. Group BFrontiers in public health · 2018
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Martina O ChukwuMSc, Department of Life and Consumer Science, School of Agriculture and Life Sciences University of South Africa (UNISA), Florida Campus, Pretoria, South Africa.
Rooyen Tinago MavenyengwaMSc, DPhil, Department of Medical Microbiology, University of Zimbabwe College of Health Sciences, Harare, Zimbabwe, Department of Health Sciences, School of Health and Applied Sciences, Polytechnic of Namibia, Windhoek, Namibia.
Charles M MonyamaMSc, Department of Life and Consumer Science, School of Agriculture and Life Sciences University of South Africa (UNISA), Florida Campus, Pretoria, South Africa.
John Y BolukaotoMSc, Department of Life and Consumer Science, School of Agriculture and Life Sciences University of South Africa (UNISA), Florida Campus, Pretoria, South Africa.
Sogolo L LebeloMSc, PhD, Department of Life and Consumer Science, School of Agriculture and Life Sciences University of South Africa (UNISA), Florida Campus, Pretoria, South Africa.
Motlatji Rb MalobaMD, Department of Microbiological Pathology, University of Limpopo (MEDUNSA), Pretoria, South Africa.
Maphoshane NchabelengMD, PhD, Department of Microbiological Pathology, University of Limpopo (MEDUNSA), Pretoria, South Africa.
Sylvester Rogers MoyoMSc, DPhil, Department of Health Sciences, School of Health and Applied Sciences, Polytechnic of Namibia, Windhoek, Namibia.
University of South Africa · ZASefako Makgatho Health Sciences University · ZAUniversity of Zimbabwe · ZW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionStreptococcus agalactiae (group B streptococcus; GBS) is globally recognised as one of the leading causes of neonatal sepsis and meningitis. It also causes adverse pregnancy outcomes such as stillbirth and miscarriages. Incidence of invasive disease is increasing in non-pregnant adults with underlying medical conditions (e.g., diabetes mellitus). Epidemiological studies of GBS infections are based on capsular serotyping. Genotyping of the surface anchored protein genes is also becoming an important tool for GBS studies. Currently ten different GBS serotypes have been identified. This study was performed to determine the prevalence of GBS capsular types (CTs) and surface anchored protein genes in isolates from colonized pregnant women attending antenatal clinic, at Dr George Mukhari Academic Hospital, Garankuwa, Pretoria, South Africa.

methodsThe samples were collected over 11 months and cultured on selective media. GBS was identified using different morphological and biochemical tests. Capsular typing was done using latex agglutination test and conventional PCR. Multiplex PCR with specific primers was used to detect the surface anchored protein genes.

resultsOf the 413 pregnant women recruited, 128 (30.9%) were colonized with GBS. The capsular polysaccharide (CPS) typing test showed that CPS type III (29.7%) was the most prevalent capsular type followed by CPS type Ia (25.8%), II (15.6%), IV (8.6%), V (10.9%) and Ib (8.6%); 0.7% of the isolates were nontypeable. Multiplex PCR revealed that the surface proteins genes were possessed by all the capsular types: rib (44.5%), bca (24.7%), alp2/3 (17.9%), epsilon (8.6%) and alp4 (4.7%).

conclusionThe common capsular types found in this study are Ia, III, and II. The most common protein genes identified were rib and bca, and the distribution of the surface protein genes among the isolates of different capsular types showed similar trends to the distribution reported from previous studies.

Indexed as

pregnancyserotypesStreptococcus agalactiaesurface proteins

Identifiers

PMID26716101
PMCPMC4691193
OpenAlexW2402830630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.