Evidence map›Paper›PMID 26716073›Full record

ReviewTissue barriers

Mechanisms of innate immunity in C. elegans epidermis.

Clara Taffoni, Nathalie Pujol

Abstract readReview
In one paragraph

Review in Tissue barriers. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Gut microbes · 2026
    Review
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  4. The Emerging Role of 3-Hydroxyanthranilic Acid onbioRxiv : the preprint server for biology · 2024
    Article
  5. Article
  6. Cells · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Treatment with paeoniflorin increases lifespan ofFrontiers in pharmacology · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Beneficial effect of Xuebijing againstFrontiers in pharmacology · 2022
    Article
  15. Take a Walk to the Wild Side ofMicrobiology and molecular biology reviews : MMBR · 2021
    Review
  16. Article
  17. Article
  18. Innate immunity in C. elegans.Current topics in developmental biology · 2021
    Review
  19. Loss of Function of Scavenger Receptor SCAV-5 ProtectsFrontiers in cellular and infection microbiology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Clara TaffoniCenter d'Immunologie de Marseille-Luminy; Aix Marseille Université UM2 ; Inserm; Marseille, France.
Nathalie PujolCenter d'Immunologie de Marseille-Luminy; Aix Marseille Université UM2 ; Inserm; Marseille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The roundworm C. elegans has been successfully used for more than 50 y as a genetically tractable invertebrate model in diverse biological fields such as neurobiology, development and interactions. C. elegans feeds on bacteria and can be naturally infected by a wide range of microorganisms, including viruses, bacteria and fungi. Most of these pathogens infect C. elegans through its gut, but some have developed ways to infect the epidermis. In this review, we will mainly focus on epidermal innate immunity, in particular the signaling pathways and effectors activated upon wounding and fungal infection that serve to protect the host. We will discuss the parallels that exist between epidermal innate immune responses in nematodes and mammals.

Indexed as

collagencuticledamageEpidermal barrierepidermisGPCRhemidesmosomepathogenPathogen-barrier interactionssignalingwounding

Identifiers

PMID26716073
PMCPMC4681281

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.