ArticleIranian journal of radiology : a quarterly journal published by the Iranian Radiological Society2015
Perianal Fistula With and Without Abscess: Assessment of Fistula Activity Using Diffusion-Weighted Magnetic Resonance Imaging.
Article in Iranian journal of radiology : a quarterly journal published by the Iranian Radiological Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 24 citations in OpenAlex.
- Diffusion Tensor Imaging in the Diagnosis of Perianal Abscess: Protocol for a Single-Blind Randomized Controlled Trial.JMIR research protocols · 2026Article
- The value of deep learning and radiomics models in predicting preoperative serosal invasion in gastric cancer: a dual-center study.Abdominal radiology (New York) · 2025Article
- The role of MRI in perianal fistulizing disease: diagnostic imaging and classification systems to monitor disease activity.Abdominal radiology (New York) · 2025Review
- Crohn's Disease-Associated and Cryptoglandular Fistulas: Differences and Similarities.Journal of clinical medicine · 2023Review
- Role of Diffusion-Weighted Imaging in the Evaluation of Perianal Fistulae.The Indian journal of radiology & imaging · 2021Article
- A comparable method to Gd-contrast enhancement in the preoperative evaluation of anal fistula.Medicine · 2019Observational
- Perianal fistula imaging: a comparison between two-channel superficial Flex coil and eight-channel body coil.Polish journal of radiology · 2019Article
- Observational
- Role of magnetic resonance imaging in the management of perianal Crohn's disease.Insights into imaging · 2018Review
- Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMagnetic resonance imaging (MRI) is highly accurate for the depiction of both the primary tract of fistula and abscesses, in patients with perianal disease. In addition, MRI can be used to evaluate the activity of fistulas, which is a significant factor for determining the therapeutic strategy.
objectivesThis study aimed to determine the usefulness of diffusion-weighted (DW) MRI for assessing activity and visibility of perianal fistula. PATIENTS AND
methodsFifty-three patients with 56 perianal fistulas were included in the current retrospective study. The T2-weighted imaging (T2WI) and DWMRI were performed and apparent diffusion coefficient (ADC) values of fistulas were measured. Fistulas were classified into two groups: only perianal fistulas and fistulas accompanied by abscess. Fistulas were also classified into two groups, based on clinical findings: positive inflammatory activity (PIA) and negative inflammatory activity (NIA).
resultsMean ADC value (mm(2)/s) of PIA group was significantly lower than that of NIA group, regarding lesions in patients with abscess-associated fistulas (1.371 × 10(-3) ± 0.168 × 10(-3) vs. 1.586 × 10(-3) ± 0.136 × 10(-3); P = 0.036). No statistically significant difference was found in mean ADC values between PIA and NIA groups, in patients with only perianal fistulas (P = 0.507). Perianal fistula visibility was greater with combined evaluation of T2WI and DWMRI than with T2WI, for two reviewers (P = 0.046 and P = 0.014).
conclusionThe DWMRI is a useful technique for evaluating activity of fistulas with abscess. Perianal fistula visibility is greater with combined T2WI and DWMRI than T2WI alone.
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