Evidence map›Paper›PMID 26715886›Full record

ArticleCurrent oncology (Toronto, Ont.)2015

A population-based study of the epidemiology of pancreatic cancer: a brief report.

R S Raju, N Coburn, N Liu, J M Porter, S J Seung, M C Cheung, N Goyert, N B Leighl, J S Hoch, M E Trudeau and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current oncology (Toronto, Ont.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  5. Article
  6. HGF/c-MET: A Promising Therapeutic Target in the Digestive System Cancers.International journal of molecular sciences · 2018
    Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

R S RajuOdette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON;
N CoburnOdette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON;
N LiuInstitute for Clinical Evaluative Sciences, Toronto, ON;
J M PorterInstitute for Clinical Evaluative Sciences, Toronto, ON;
S J SeungHealth Outcomes and PharmacoEconomics Research Centre, Sunnybrook Research Institute, Toronto, ON;
M C CheungOdette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON;
N GoyertOdette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON;
N B LeighlPrincess Margaret Cancer Centre, University Health Network, Toronto, ON;
J S HochApplied Research in Cancer Control, Cancer Care Ontario, Toronto, ON;
M E TrudeauOdette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON;
W K EvansMcMaster University, Hamilton, ON;
K N DaintyKeenan Research Centre of the Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON;
C C EarleOdette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON;
N MittmannHealth Outcomes and PharmacoEconomics Research Centre, Sunnybrook Research Institute, Toronto, ON; ; Department of Pharmacology, University of Toronto, Toronto, ON; ; International Centre for Health Innovation, Richard Ivey School of Business, Western University, London, ON.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAdministrative data are used to describe the pancreatic cancer (pcc) population. The analysis examines demographic details, incidence, site, survival, and factors influencing mortality in a cohort of individuals diagnosed with pcc.

methodsIncident cases of pcc diagnosed in Ontario between 1 January 2004 and 31 December 2011 were extracted from the Ontario Cancer Registry. They were linked by encrypted health card number to several administrative databases to obtain demographic and mortality information. Descriptive, bivariate, and survival analyses were conducted.

resultsDuring the period of interest, 9221 new cases of pcc (4548 in men, 4673 in women) were diagnosed, for an age-adjusted standardized annual incidence in the range of 8.6-9.5 per 100,000 population. Mean age at diagnosis was 70.3 ± 12.5 years (standard deviation). Five-year survival was 7.2% (12.8% for those <60 years of age and 3.6% for those >80 years of age). Survival varied by sex, older age, rural residence, lower income, site of involvement in the pancreas, and presence of comorbidity.

conclusionsThe mortality rate in pcc is exceptionally high. With an increasing incidence and a mortality positively associated with age, additional support will be needed for this highly fatal disease as demographics in Ontario continue to trend toward a higher proportion of older individuals.

Indexed as

outcomesPancreatic adenocarcinomapopulation studiesretrospective analyses

Identifiers

PMID26715886
PMCPMC4687674

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.