Evidence map›Paper›PMID 26715824›Full record

SynthesisWorld journal of gastroenterology2015

Effect of intraperitoneal local anesthetic on pain characteristics after laparoscopic cholecystectomy.

Geun Joo Choi, Hyun Kang, Chong Wha Baek, Yong Hun Jung, Dong Rim Kim

Abstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 6 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 6 syntheses or guidelines pooled it, 70 citations in OpenAlex.

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  15. Use of Intraperitoneal Lidocaine in Horses Undergoing Laparotomy for Colic.Animals : an open access journal from MDPI · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Geun Joo ChoiGeun Joo Choi, Hyun Kang, Chong Wha Baek, Yong Hun Jung, Dong Rim Kim, Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul 06911, South Korea.
Hyun KangGeun Joo Choi, Hyun Kang, Chong Wha Baek, Yong Hun Jung, Dong Rim Kim, Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul 06911, South Korea.
Chong Wha BaekGeun Joo Choi, Hyun Kang, Chong Wha Baek, Yong Hun Jung, Dong Rim Kim, Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul 06911, South Korea.
Yong Hun JungGeun Joo Choi, Hyun Kang, Chong Wha Baek, Yong Hun Jung, Dong Rim Kim, Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul 06911, South Korea.
Dong Rim KimGeun Joo Choi, Hyun Kang, Chong Wha Baek, Yong Hun Jung, Dong Rim Kim, Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul 06911, South Korea.
Chung-Ang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo systematically evaluate the effect of intraperitoneal local anesthetic on pain characteristics after laparoscopic cholecystectomy (LC).

methodsWe searched MEDLINE, EMBASE, and the Cochrane Library. Randomized controlled trials in English that compared the effect of intraperitoneal administration of local anesthetics on pain with that of placebo or nothing after elective LC under general anesthesia were included. The primary outcome variables analyzed were the combined scores of abdominal, visceral, parietal, and shoulder pain after LC at multiple time points. We also extracted pain scores at resting and dynamic states.

resultsWe included 39 studies of 3045 patients in total. The administration of intraperitoneal local anesthetic reduced pain intensity in a resting state after laparoscopic cholecystectomy: abdominal [standardized mean difference (SMD) = -0.741; 95%CI: -1.001 to -0.48, P < 0.001]; visceral (SMD = -0.249; 95%CI: -0.493 to -0.006, P = 0.774); and shoulder (SMD = -0.273; 95%CI: -0.464 to -0.082, P = 0.097). Application of intraperitoneal local anesthetic significantly reduced the incidence of shoulder pain (RR = 0.437; 95%CI: 0.299 to 0.639, P < 0.001). There was no favorable effect on resting parietal or dynamic abdominal pain.

conclusionIntraperitoneal local anesthetic as an analgesic adjuvant in patients undergoing laparoscopic cholecystectomy exhibited beneficial effects on postoperative abdominal, visceral, and shoulder pain in a resting state.

Indexed as

Abdominal PainAnalgesicsAnesthetics, LocalCholecystectomy, LaparoscopicDrug Administration RoutesHumansPain MeasurementPostoperative PainRisk FactorsShoulder PainTreatment OutcomeVisceral PainAnalgesicsAnesthetics, LocalIntraperitonealLaparoscopic cholecystectomyLocal anestheticMeta-analysisPain

Identifiers

PMID26715824
PMCPMC4679773
OpenAlexW2221728779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.