ArticleInfection ecology & epidemiology2015
First identification of methicillin-resistant Staphylococcus pseudintermedius strains among coagulase-positive staphylococci isolated from dogs with otitis externa in Trinidad, West Indies.
Article in Infection ecology & epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 18 citations in OpenAlex.
- Prevalence and genotypic characterization of Methicillin-Resistant Staphylococcus aureus (MRSA) harboring femA and tetM in canine and feline otitis externa.Scientific reports · 2026Article
- Culture and Metagenomic Insights into the Ear Microbiota in Dogs with Healthy Ears and Otitis Externa.Veterinary sciences · 2026Article
- Emergence of methicillin resistantFrontiers in veterinary science · 2026Article
- Bacterial Agents and Antimicrobial-Resistance Patterns in Canine Otitis Externa.Animals : an open access journal from MDPI · 2025Article
- Global phylogenomic analysis ofMicrobial genomics · 2025Article
- Antibacterial Effect of Canine Leucocyte Platelet-Rich Plasma (L-PRP) and Canine Platelet-Poor Plasma (PPP) Against Methicillin-Sensitive and Methicillin-ResistantVeterinary sciences · 2024Article
- Phenotypic and genotypic detection of multi drug resistant coagulase-positiveIranian journal of veterinary research · 2024Article
- Virulence Mechanisms of Staphylococcal Animal Pathogens.International journal of molecular sciences · 2023Review
- Nasal microbiota profiles in shelter dogs with dermatological conditions carrying methicillin-resistant and methicillin-sensitive Staphylococcus species.Scientific reports · 2023Article
- Article
- Patterns of antimicrobial, multidrug and methicillin resistance among Staphylococcus spp. isolated from canine specimens submitted to a diagnostic laboratory in Tennessee, USA: a descriptive study.BMC veterinary research · 2022Article
- The Complex Diseases ofVeterinary sciences · 2021Review
- Article
- Antimicrobial resistance patterns of bacteria isolated from dogs with otitis.Epidemiology and infection · 2019Article
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Authors and funding
7 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOtitis externa is a common inflammatory ear disease in dogs caused by a variety of pathogens, and coagulase-positive staphylococci are frequently isolated from such infections.
objectiveTo identify antimicrobial susceptibility profiles and methicillin-resistant strains among coagulase-positive staphylococci isolated from otitis externa in dogs.
methodsA cross-sectional study was performed over 2 years on 114 client-owned dogs presented to the Veterinary Teaching Hospital with a primary complaint of ear infections. Swabs were obtained from both ears and cultured for staphylococci which were subsequently confirmed as coagulase-positive using rabbit plasma. Antimicrobial susceptibility assays were assessed on all isolates followed by subsequent genetic analysis for species identification and detection of the mecA gene.
resultsSixty-five coagulase-positive staphylococci were isolated from 114 client-owned dogs. The isolates exhibited resistance against neomycin (58.5%), streptomycin (49.2%), penicillin (49.2%), polymyxin B (44.6%), tetracycline (36.9%), sulphamethoxazole/trimethoprim (33.8%), kanamycin (33.8%), doxycycline (32.3%), norfloxacin (23.1%), amoxicillin/clavulanate (20%), ciprofloxacin (20%), enrofloxacin (18.5%), gentamicin (16.9%), and cephalothin (9.2%). Forty (61.5%) of the isolates were resistant to at least three or more antimicrobials and 10 were sensitive to all. Using a multiplex polymerase chain reaction assay based on species-specific regions of the thermonuclease (nuc) gene, 38/65 (58.5%) isolates were classified as Staphylococcus aureus, 23/65 (35.4%) as S. pseudintermedius, 2/65 (3.1%) as S. intermedius, and 2/65 (3.1%) as S. schleiferi. Analysis for the mecA gene revealed two positive isolates of S. pseudintermedius which were oxacillin-resistant, representing a first report of such organisms in the Caribbean.
conclusionDespite the relatively high prevalence of multidrug-resistant coagulase-positive staphylococci in Trinidad, these are largely susceptible to gentamicin consistent with use in clinical practice. The first detection of methicillin-resistant S. pseudintermedius (MRSP) in dogs is likely to have implications on the treatment options for otitis externa in dogs and potential public health significance.
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