Evidence map›Paper›PMID 26714883›Full record

ArticleJournal of the International Neuropsychological Society : JINS2016

Prospective, Head-to-Head Study of Three Computerized Neurocognitive Assessment Tools (CNTs): Reliability and Validity for the Assessment of Sport-Related Concussion.

Lindsay D Nelson, Ashley A LaRoche, Adam Y Pfaller, E Brooke Lerner, Thomas A Hammeke, Christopher Randolph, William B Barr, Kevin Guskiewicz, Michael A McCrea

Abstract read
In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lindsay D Nelson1Medical College of Wisconsin,Milwaukee,Wisconsin.
Ashley A LaRoche1Medical College of Wisconsin,Milwaukee,Wisconsin.
Adam Y Pfaller1Medical College of Wisconsin,Milwaukee,Wisconsin.
E Brooke Lerner1Medical College of Wisconsin,Milwaukee,Wisconsin.
Thomas A Hammeke1Medical College of Wisconsin,Milwaukee,Wisconsin.
Christopher Randolph3Loyola University Medical School,Maywood,Illinois.
William B Barr4New York University School of Medicine,New York,New York.
Kevin Guskiewicz5University of North Carolina at Chapel Hill,Chapel Hill,NC.
Michael A McCrea1Medical College of Wisconsin,Milwaukee,Wisconsin.

Funding

Clincal and Translational Science AwardUL1TR000055 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI SHAKER, REZA NONE · 2012 to 2015
$11.3M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR031973 · NCRR · MEDICAL COLLEGE OF WISCONSIN · PI SHAKER, REZA NONE · 2010 to 2011
$7.9M
NCATS NIH HHS 8UL1TR000055NCATS NIH HHS UL1 TR000055NCRR NIH HHS 1UL1-RR031973-01NCRR NIH HHS UL1 RR031973
6 · The paper itself

Abstract

Limited data exist comparing the performance of computerized neurocognitive tests (CNTs) for assessing sport-related concussion. We evaluated the reliability and validity of three CNTs-ANAM, Axon Sports/Cogstate Sport, and ImPACT-in a common sample. High school and collegiate athletes completed two CNTs each at baseline. Concussed (n=165) and matched non-injured control (n=166) subjects repeated testing within 24 hr and at 8, 15, and 45 days post-injury. Roughly a quarter of each CNT's indices had stability coefficients (M=198 day interval) over .70. Group differences in performance were mostly moderate to large at 24 hr and small by day 8. The sensitivity of reliable change indices (RCIs) was best at 24 hr (67.8%, 60.3%, and 47.6% with one or more significant RCIs for ImPACT, Axon, and ANAM, respectively) but diminished to near the false positive rates thereafter. Across time, the CNTs' sensitivities were highest in those athletes who became asymptomatic within 1 day before neurocognitive testing but was similar to the tests' false positive rates when including athletes who became asymptomatic several days earlier. Test-retest reliability was similar among these three CNTs and below optimal standards for clinical use on many subtests. Analyses of group effect sizes, discrimination, and sensitivity and specificity suggested that the CNTs may add incrementally (beyond symptom scores) to the identification of clinical impairment within 24 hr of injury or within a short time period after symptom resolution but do not add significant value over symptom assessment later. The rapid clinical recovery course from concussion and modest stability probably jointly contribute to limited signal detection capabilities of neurocognitive tests outside a brief post-injury window. (JINS, 2016, 22, 24-37).

Indexed as

Neuropsychological TestsAdolescentAnalysis of VarianceAthletic InjuriesBrain ConcussionCognition DisordersDiagnosis, Computer-AssistedFemaleHumansMaleReaction TimeReproducibility of ResultsROC CurveTrauma Severity IndicesYoung AdultANAMAxon SportsComputerized testingConcussionImPACTSport

Identifiers

PMID26714883
PMCPMC4882608

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.