ArticleSocial cognitive and affective neuroscience2016
Amygdala and dorsomedial hyperactivity to emotional faces in youth with remitted Major Depression.
Article in Social cognitive and affective neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Balancing act: Neural correlates of affect dysregulation in youth depression and substance use - A systematic review of functional neuroimaging studies.Developmental cognitive neuroscience · 2020Pooled it
- Loneliness is related to facial emotion perception in people with HIV.Scientific reports · 2025Article
- Relationship between brain structural network integrity and emotional symptoms in youth with perinatally-acquired HIV.Brain, behavior, and immunity · 2024Article
- Relationship of prefrontal cortex activity with anhedonia and cognitive function in major depressive disorder: an fNIRS study.Frontiers in psychiatry · 2024Article
- Human emotion processing accuracy, negative biases, and fMRI activation are associated with childhood trauma.Frontiers in psychiatry · 2023Article
- Functional connectivity of the right inferior frontal gyrus and orbitofrontal cortex in depression.Social cognitive and affective neuroscience · 2020Article
- Predictors of Attrition in Longitudinal Neuroimaging Research: Inhibitory Control, Head Movement, and Resting-State Functional Connectivity.Brain connectivity · 2018Article
- Reliability, Convergent Validity and Time Invariance of Default Mode Network Deviations in Early Adult Major Depressive Disorder.Frontiers in psychiatry · 2018Article
- Considering sex differences clarifies the effects of depression on facial emotion processing during fMRI.Journal of affective disorders · 2018Article
- Affective traits and history of depression are related to ventral striatum connectivity.Journal of affective disorders · 2017Article
- Measuring Pain for Patients Seeking Physical Therapy: Can Functional Magnetic Resonance Imaging (fMRI) Help?Physical therapy · 2017Article
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15 authors at 4 institutions in 1 country.
Funding
Abstract
We present neuroimaging markers of the remitted state of major depressive disorder (rMDD) during facial emotion perception in 84 individuals during fMRI. Participants comprised 47 individuals (aged 18-23) diagnosed with rMDD and 37 healthy controls (HCs). Participants classified emotional faces or animals (control condition) in the Facial Emotion Perception Test (FEPT) during fMRI. Behavioural performance on the FEPT did not differ significantly between groups. During fMRI, both groups demonstrated significant blood oxygen level-dependent (BOLD) activity in bilateral inferior frontal gyri for the faces minus animals (F-A) contrast. The rMDD group additionally showed BOLD activity during F-A in numerous regions, including the bilateral paracingulate gyri, middle temporal gyri and right amygdala. The rMDD group exhibited significantly greater activity than the HC group in regions including the bilateral middle temporal gyri and left superior frontal gyrus. Although the rMDD group did not manifest the behavioural performance deficits on facial emotion recognition tasks that have been observed in actively depressed individuals, the rMDD group nevertheless showed increased BOLD activity compared with never-depressed controls during F-A in multiple posterior brain regions, suggesting that persistent effects of illness or possible trait vulnerabilities may distinguish individuals with rMDD from never-depressed controls.
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