Evidence map›Paper›PMID 26714464›Full record

ArticleJournal of orthopaedic surgery and research2015

Accuracy of cartilage-specific 3-Tesla 3D-DESS magnetic resonance imaging in the diagnosis of chondral lesions: comparison with knee arthroscopy.

Sandro Kohl, Simon Meier, Sufian S Ahmad, Harald Bonel, Aristomenis K Exadaktylos, Anna Krismer, Dimitrios Stergios Evangelopoulos

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of orthopaedic surgery and research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Magnetic resonance imaging is able to detect patellofemoral focal cartilage injuries: a systematic review with meta-analysis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023
    Pooled it
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  6. Longitudinal In Vivo 3T MRI of Naturally Occurring Early Osteochondrosis Lesions in the Piglet Humeral Epiphyseal Cartilage and Growth Plate.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
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  11. Correction of BNMR in biomedicine · 2023
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  12. Review
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  14. Increase in cartilage degeneration in all knee compartments after failed ACL reconstruction at 4 years of follow-up.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Sandro KohlDepartment of Orthopaedic Surgery, Inselspital, University of Bern, Freiburgstrasse, CH-3010, Bern, Switzerland. sandro.kohl@gmail.com.
Simon MeierDepartment of Orthopaedic Surgery, Inselspital, University of Bern, Freiburgstrasse, CH-3010, Bern, Switzerland. simon.meier@insel.ch.
Sufian S AhmadDepartment of Orthopaedic Surgery, Inselspital, University of Bern, Freiburgstrasse, CH-3010, Bern, Switzerland. sufiansamy@gmail.com.
Harald BonelDepartment of Diagnostic, Interventional and Pediatric Radiology, Inselspital, University of Bern, Freiburgstrasse, Bern, CH-3010, Switzerland. herald.bonel@insel.ch.
Aristomenis K ExadaktylosDepartment of Emergency Medicine, Inselspital, University of Bern, Freiburgstrasse, Bern, CH-3010, Switzerland. aristomenis.exadaktylos@insel.ch.
Anna KrismerDepartment of Orthopaedic Surgery, Inselspital, University of Bern, Freiburgstrasse, CH-3010, Bern, Switzerland. anna.krismer@insel.ch.
Dimitrios Stergios EvangelopoulosDepartment of Orthopaedic Surgery, Inselspital, University of Bern, Freiburgstrasse, CH-3010, Bern, Switzerland. ds.evangelopoulos@gmail.com.
University of Bern · CHUniversity Hospital of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArthroscopy is considered as "the gold standard" for the diagnosis of traumatic intraarticular knee lesions. However, recent developments in magnetic resonance imaging (MRI) now offer good opportunities for the indirect assessment of the integrity and structural changes of the knee articular cartilage. The study was to investigate whether cartilage-specific sequences on a 3-Tesla MRI provide accurate assessment for the detection of cartilage defects.

methodsA 3-Tesla (3-T) MRI combined with three-dimensional double-echo steady-state (3D-DESS) cartilage specific sequences was performed on 210 patients with knee pain prior to knee arthroscopy. Sensitivity, specificity, and positive and negative predictive values of magnetic resonance imaging were calculated and correlated to the arthroscopic findings of cartilaginous lesions. Lesions were classified using the modified Outerbridge classification.

resultsFor the 210 patients (1260 cartilage surfaces: patella, trochlea, medial femoral condyle, medial tibia, lateral femoral condyle, lateral tibia) evaluated, the sensitivities, specificities, positive predictive values, and negative predictive values of 3-T MRI were 83.3, 99.8, 84.4, and 99.8 %, respectively, for the detection of grade IV lesions; 74.1, 99.6, 85.2, and 99.3 %, respectively, for grade III lesions; 67.9, 99.2, 76.6, and 98.2 %, respectively, for grade II lesions; and 8.8, 99.5, 80, and 92 %, respectively, for grade I lesions.

conclusionsFor grade III and IV lesions, 3-T MRI combined with 3D-DESS cartilage-specific sequences represents an accurate diagnostic tool. For grade II lesions, the technique demonstrates moderate sensitivity, while for grade I lesions, the sensitivity is limited to provide reliable diagnosis compared to knee arthroscopy.

Indexed as

AdolescentAdultAgedAged, 80 and overArthroscopyCartilage, ArticularFemaleHumansImaging, Three-DimensionalKnee JointMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesYoung Adult

Identifiers

PMID26714464
PMCPMC4696275
OpenAlexW2214697235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.