Evidence map›Paper›PMID 26714435›Full record

ArticleCardiology in the young2016

Impact of postoperative complications on hospital costs following the Norwood operation.

Kimberly E McHugh, Sara K Pasquali, Matthew A Hall, Mark A Scheurer

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Cardiology in the young, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Cost Variation Across Centers for the Norwood Operation.The Annals of thoracic surgery · 2018
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Kimberly E McHugh1Medical University of South Carolina,Charleston,South Carolina,United States of America.ORCID http://orcid.org/0000-0001-8329-5411
Sara K Pasquali2University of Michigan CS Mott Children's Hospital,Ann Arbor,Michigan,United States of America.
Matthew A Hall3Children's Hospital Association,Overland Park,Kansas,United States of America.
Mark A Scheurer1Medical University of South Carolina,Charleston,South Carolina,United States of America.
Medical University of South Carolina · USChildren's Hospital Association · USC. S. Mott Children's Hospital · US

Funding

Pediatric Heart network DCCU10HL068270 · NHLBI · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MILLER, JULIE ELAINE, TRACHTENBERG, FELICIA LYNN · 2011 to 2016
$44.9M
Pediatric Heart Network Medical University of South CarolinaU10HL109778 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ATZ, ANDREW M, GRAHAM, ERIC M. · 2011 to 2015
$2.2M
NHLBI NIH HHS U10 HL068270NHLBI NIH HHS U10 HL109778
6 · The paper itself

Abstract

unlabelledIntroduction Patients undergoing the Norwood operation consume considerable healthcare resources; however, detailed information regarding factors impacting hospitalisation costs is lacking. We evaluated the association of postoperative complications with hospital costs.

methodsIn the present study, we utilised a unique data set consisting of prospectively collected clinical data from the Pediatric Heart Network Single Ventricle Reconstruction trial linked at the patient level with cost data for 10 hospitals participating in the Children's Hospital Association Case Mix database during the trial period. The relationship between complications and cost was modelled using linear regression, accounting for the skewed distribution of cost, adjusting for within-centre clustering and baseline patient characteristics.

resultsA total of 334 eligible Norwood records (97.5%) were matched between data sets. Overall, 82% suffered from at least one complication (median 2; with a range from 0 to 33). Those with complications had longer postoperative length of stay (25 versus 12 days, p<0.001), more total ventilator days (7 versus 5 days, p<0.001), and higher in-hospital mortality (17.6 versus 3.4%, p<0.006). Mean adjusted hospital cost in those with a complication was $190,689 (95% CI $111,344-$326,577) versus $120,584 (95% CI $69,246-$209,983) in those without complications (p=0.002). Costs increased with the number of complications (1-2 complications=$132,800 versus 3-4 complications=$182,353 versus ⩾5 complications=$309,372 [p<0.001]).

conclusionsThis merged data set of clinical trial and cost data demonstrated that postoperative complications are common following the Norwood operation and are associated with worse clinical outcomes and higher costs. Efforts to reduce complications in this population may lead to improved outcomes and cost savings.

Indexed as

Databases, FactualFemaleHospital CostsHospital MortalityHospitals, PediatricHumansHypoplastic Left Heart SyndromeInfantLength of StayMaleNorwood ProceduresPostoperative ComplicationsPrenatal DiagnosisTreatment OutcomeUnited Statescomplicationshypoplastic left heart syndromeNorwood operationresource utilisation

Identifiers

PMID26714435
PMCPMC6383204
OpenAlexW2220064139

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.