Evidence map›Paper›PMID 26714431›Full record

ReviewNature reviews. Microbiology2016

The biogeography of polymicrobial infection.

Apollo Stacy, Luke McNally, Sophie E Darch, Sam P Brown, Marvin Whiteley

Abstract readReview
In one paragraph

Review in Nature reviews. Microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 172 papers.

0numbers the graph read from it
0cells of the map it votes in
172citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

172 citing papers in PubMed.

  1. Article
  2. Review
  3. Biophysical Constraints Dictate the Stability of Social Traits inbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
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  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Biofilm comes back: Controlling regrowth by mitigating the cell-matrix interaction.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2025
    Article
  20. Article

112 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Apollo StacyDepartment of Molecular Biosciences, Institute of Cellular and Molecular Biology, Center for Infectious Disease, The University of Texas at Austin, 1 University Station A5000, Austin, Texas 78712, USA.
Luke McNallyCentre for Immunity, Infection and Evolution, School of Biological Sciences, The University of Edinburgh, Edinburgh EH9 3FL, UK.
Sophie E DarchDepartment of Molecular Biosciences, Institute of Cellular and Molecular Biology, Center for Infectious Disease, The University of Texas at Austin, 1 University Station A5000, Austin, Texas 78712, USA.
Sam P BrownSchool of Biology, Georgia Institute of Technology, Atlanta, Georgia 30332-0230, USA.
Marvin WhiteleyDepartment of Molecular Biosciences, Institute of Cellular and Molecular Biology, Center for Infectious Disease, The University of Texas at Austin, 1 University Station A5000, Austin, Texas 78712, USA.

Funding

Metabolite sensing in a polymicrobial infectionR01DE020100 · NIDCR · UNIVERSITY OF TEXAS AT AUSTIN · PI WHITELEY, MARVIN · 2011 to 2022
$3.3M
Mechanisms of Pseudomonas aeruginosa virulence in polymicrobial wound infectionsR01GM116547 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI WHITELEY, MARVIN · 2016 to 2019
$1.2M
NIDCR NIH HHS 1R01DE020100NIDCR NIH HHS R01 DE020100NIGMS NIH HHS R01 GM116547
6 · The paper itself

Abstract

Microbial communities are spatially organized in both the environment and the human body. Although patterns exhibited by these communities are described by microbial biogeography, this discipline has previously only considered large-scale, global patterns. By contrast, the fine-scale positioning of a pathogen within an infection site can greatly alter its virulence potential. In this Review, we highlight the importance of considering spatial positioning in the study of polymicrobial infections and discuss targeting biogeography as a therapeutic strategy.

Indexed as

BiofilmsCoinfectionEpitheliumHumansPhylogeographySymbiosis

Identifiers

PMID26714431
PMCPMC5116812

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.