ReviewHead & neck2016
Cervical lymph node metastases from remote primary tumor sites.
Review in Head & neck, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 131 citations in OpenAlex.
- Occult squamous cell carcinoma presenting as oligometastatic lymphadenopathy. A systematic review with a case report.Oncology reviews · 2026Pooled it
- Contrast-enhanced ultrasound (CEUS) in characterization of inconclusive cervical lymph nodes: a meta-analysis and systematic review.Scientific reports · 2022Pooled it
- Head and Neck Metastases From Infraclavicular Primary Tumors: Analysis of 136 Cases.The Laryngoscope · 2026Article
- Article
- Schwannoma Mimicking Neck Nodal Metastasis on F-18 FDG PET/CT in Cervical Cancer: A Case Report with a Multimodal Approach.Diagnostics (Basel, Switzerland) · 2026Article
- Metastatic Tumors from Unknown Primary in Cervical Lymph Nodes: A Decade of Study in a Tertiary Care Center of a Resource-Limited Country.JNMA; journal of the Nepal Medical Association · 2026Article
- Nomogram for predicting urinary retention after radical hysterectomy for cervical cancer with comparative analysis of surgical methods.Pakistan journal of medical sciences · 2025Article
- Evaluation of the Frequency and Patterns of Cervical Cancer Recurrence After Treatment Using ^18F-FDG PET-CT: A Cross-Sectional Study.Health science reports · 2025Article
- Multimodal imaging of cervical lymphadenopathy: diagnostic value and clinical applications.Medicine and pharmacy reports · 2025Review
- Clinical Characteristics and Survival Analysis of Patients with Supraclavicular Fossa Lymphadenopathy.Diagnostics (Basel, Switzerland) · 2025Article
- Feasibility, efficacy, and safety of core needle biopsy as a first-line method for cervical lymphadenopathy.European radiology · 2025Article
- When neck lymph nodes metastases do not origin from a head and neck unknown primary.Current opinion in otolaryngology & head and neck surgery · 2025Review
- Supraclavicular nodal metastasis at primary staging of prostate cancer usingEJNMMI reports · 2025Article
- Cervical Lymph Node Metastasis of Unknown Origin and Remote Primary at a Tertiary Cancer Centre in North India: Case Series with Review of Literature.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Unusual Metastatic Pathways: A Case of Colorectal Adenocarcinoma Presenting as a Cervical Neck Mass.Cureus · 2024Article
- A deep learning method for predicting the origins of cervical lymph node metastatic cancer on digital pathological images.iScience · 2024Article
- Eugenol as a potential adjuvant therapy for gingival squamous cell carcinoma.Scientific reports · 2024Article
- Head and neck cancer of unknown primary: unveiling primary tumor sites through machine learning on DNA methylation profiles.Clinical epigenetics · 2024Article
- Utility of UV Signature Mutations in the Diagnostic Assessment of Metastatic Head and Neck Carcinomas of Unknown Primary.Head and neck pathology · 2024Article
- Optimal Extent of Neck Dissection for a Head and Neck Lymph Node Metastasis from a Remote Primary Site.Journal of clinical medicine · 2024Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 13 institutions in 8 countries.
Funding
Abstract
Although most malignant lymphadenopathy in the neck represent lymphomas or metastases from head and neck primary tumors, occasionally, metastatic disease from remote, usually infraclavicular, sites presents as cervical lymphadenopathy with or without an obvious primary tumor. In general, these tumors metastasize to supraclavicular lymph nodes, but occasionally may present at an isolated higher neck level. A search for the primary tumor includes information gained by histology, immunohistochemistry, and evaluation of molecular markers that may be unique to the primary tumor site. In addition, 18F-fluoro-2-deoxyglocose positron emission tomography combined with CT (FDG-PET/CT) has greatly improved the ability to detect the location of an unknown primary tumor, particularly when in a remote location. Although cervical metastatic disease from a remote primary site is often incurable, there are situations in which meaningful survival can be achieved with appropriate local treatment. Management is quite complex and requires a truly multidisciplinary approach. © 2015 Wiley Periodicals, Inc. Head Neck 38: E2374-E2385, 2016.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.