Evidence map›Paper›PMID 26713226›Full record

ArticlePeerJ2015

Swarm v2: highly-scalable and high-resolution amplicon clustering.

Frédéric Mahé, Torbjørn Rognes, Christopher Quince, Colomban de Vargas, Micah Dunthorn

Abstract read
In one paragraph

Article in PeerJ, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 192 papers.

0numbers the graph read from it
0cells of the map it votes in
192citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

192 citing papers in PubMed.

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  17. Three-dimensional conservation planning of fish biodiversity metrics to achieve the deep-sea 30×30 conservation target.Conservation biology : the journal of the Society for Conservation Biology · 2025
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132 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Frédéric MahéDepartment of Ecology, Technische Universität Kaiserslautern , Kaiserslautern , Germany.
Torbjørn RognesDepartment of Informatics, University of Oslo , Oslo , Norway ; Department of Microbiology, Oslo University Hospital, Rikshospitalet , Oslo , Norway.
Christopher QuinceWarwick Medical School, University of Warwick , Warwick , United Kingdom.
Colomban de VargasUMR 7144, EPEP-Évolution des Protistes et des Écosystèmes Pélagiques, Station Biologique de Roscoff, CNRS , Roscoff , France ; UMR7144 Station Biologique de Roscoff, Sorbonne Universités, UPMC Univ Paris 06 , Roscoff , France.
Micah DunthornDepartment of Ecology, Technische Universität Kaiserslautern , Kaiserslautern , Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previously we presented Swarm v1, a novel and open source amplicon clustering program that produced fine-scale molecular operational taxonomic units (OTUs), free of arbitrary global clustering thresholds and input-order dependency. Swarm v1 worked with an initial phase that used iterative single-linkage with a local clustering threshold (d), followed by a phase that used the internal abundance structures of clusters to break chained OTUs. Here we present Swarm v2, which has two important novel features: (1) a new algorithm for d = 1 that allows the computation time of the program to scale linearly with increasing amounts of data; and (2) the new fastidious option that reduces under-grouping by grafting low abundant OTUs (e.g., singletons and doubletons) onto larger ones. Swarm v2 also directly integrates the clustering and breaking phases, dereplicates sequencing reads with d = 0, outputs OTU representatives in fasta format, and plots individual OTUs as two-dimensional networks.

Indexed as

BarcodingEnvironmental diversityMolecular operational taxonomic units

Identifiers

PMID26713226
PMCPMC4690345

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.