Evidence map›Paper›PMID 26713216›Full record

ArticleBiomedical optics express2015

OCT-based crystalline lens topography in accommodating eyes.

Pablo Pérez-Merino, Miriam Velasco-Ocana, Eduardo Martinez-Enriquez, Susana Marcos

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 57 citations in OpenAlex.

  1. Crystalline Lens Shape During Accommodation in Children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  2. Article
  3. Article
  4. In vivo assessment of multifocal contact lens fitting using anterior segment optical coherence tomography.Contact lens & anterior eye : the journal of the British Contact Lens Association · 2025
    Article
  5. Optical and Visual Diet in Myopia.Investigative ophthalmology & visual science · 2025
    Review
  6. Crystalline lens power and astigmatism calculation in myopia by swept-source optical coherence tomography: A pilot study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  7. Article
  8. Article
  9. Accommodating version of a schematic eye for emmetropia and myopia.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
  10. Article
  11. Article
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  15. Article
  16. Article
  17. Article
  18. Biomedical optics express · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Pablo Pérez-MerinoInstituto de Óptica "Daza de Valdés," Consejo Superior de Investigaciones Científicas, C/Serrano 121, 28006 Madrid, Spain.
Miriam Velasco-OcanaInstituto de Óptica "Daza de Valdés," Consejo Superior de Investigaciones Científicas, C/Serrano 121, 28006 Madrid, Spain.
Eduardo Martinez-EnriquezInstituto de Óptica "Daza de Valdés," Consejo Superior de Investigaciones Científicas, C/Serrano 121, 28006 Madrid, Spain.
Susana MarcosInstituto de Óptica "Daza de Valdés," Consejo Superior de Investigaciones Científicas, C/Serrano 121, 28006 Madrid, Spain.
Consejo Superior de Investigaciones Científicas · ESInstituto de Óptica "Daza de Valdés" · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Custom Spectral Domain Optical Coherence Tomography (SD-OCT) provided with automatic quantification and distortion correction algorithms was used to measure anterior and posterior crystalline lens surface elevation in accommodating eyes and to evaluate relationships between anterior segment surfaces. Nine young eyes were measured at different accommodative demands. Anterior and posterior lens radii of curvature decreased at a rate of 0.78 ± 0.18 and 0.13 ± 0.07 mm/D, anterior chamber depth decreased at 0.04 ± 0.01 mm/D and lens thickness increased at 0.04 ± 0.01 mm/D with accommodation. Three-dimensional surface elevations were estimated by subtracting best fitting spheres. In the relaxed state, the spherical term accounted for most of the surface irregularity in the anterior lens (47%) and astigmatism (70%) in the posterior lens. However, in accommodated lenses astigmatism was the predominant surface irregularity (90%) in the anterior lens. The RMS of high-order irregularities of the posterior lens surface was statistically significantly higher than that of the anterior lens surface (x2.02, p<0.0001). There was significant negative correlation in vertical coma (Z3 (-1)) and oblique trefoil (Z3 (-3)) between lens surfaces. The astigmatic angle showed high degree of alignment between corneal surfaces, moderate between corneal and anterior lens surface (~27 deg), but differed by ~80 deg between the anterior and posterior lens surfaces (including relative anterior/posterior lens astigmatic angle shifts (10-20 deg).

Indexed as

(100.2960) Image analysis(110.4500) Optical coherence tomography(110.6880) Three-dimensional image acquisition(120.6650) Surface measurements, figure(330.7322) Visual optics, accommodation(330.7323) Visual optics, aging changes(330.7327) Visual optics, ophthalmic instrumentation

Identifiers

PMID26713216
PMCPMC4679276
OpenAlexW2325513037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.