ArticleBiomedical optics express2015
Quantitative spatial frequency fluorescence imaging in the sub-diffusive domain for image-guided glioma resection.
Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 29 citations in OpenAlex.
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- Speckle-illumination spatial frequency domain imaging with a stereo laparoscope for profile-corrected optical property mapping.Journal of biomedical optics · 2025Article
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- Multimodal imaging needle combining optical coherence tomography and fluorescence for imaging of live breast cancer cells labeled with a fluorescent analog of tamoxifen.Journal of biomedical optics · 2022Article
- Perspective on the integration of optical sensing into orthopedic surgical devices.Journal of biomedical optics · 2022Article
- Handheld multispectral imager for quantitative skin assessment in low-resource settings.Journal of biomedical optics · 2020Article
- Wide-field optical spectroscopy system integrating reflectance and spatial frequency domain imaging to measure attenuation-corrected intrinsic tissue fluorescence in radical prostatectomy specimens.Biomedical optics express · 2020Article
- Spatial frequency domain imaging in 2019: principles, applications, and perspectives.Journal of biomedical optics · 2019Review
- Quantitative subsurface spatial frequency-domain fluorescence imaging for enhanced glioma resection.Journal of biophotonics · 2019Article
- Single snapshot of optical properties image quality improvement using anisotropic two-dimensional windows filtering.Journal of biomedical optics · 2019Article
- Multi-beam scan analysis with a clinical LINAC for high resolution Cherenkov-excited molecular luminescence imaging in tissue.Biomedical optics express · 2018Article
- Review of structured light in diffuse optical imaging.Journal of biomedical optics · 2018Review
- Optical Characterization of Neurosurgical Operating Microscopes: Quantitative Fluorescence and Assessment of PpIX Photobleaching.Scientific reports · 2018Article
- Calibration and analysis of a multimodal micro-CT and structured light imaging system for the evaluation of excised breast tissue.Physics in medicine and biology · 2017Article
- Real-time endoscopic optical properties imaging.Biomedical optics express · 2017Article
- qF-SSOP: real-time optical property corrected fluorescence imaging.Biomedical optics express · 2017Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Intraoperative 5- aminolevulinic acid induced-Protoporphyrin IX (PpIX) fluorescence guidance enables maximum safe resection of glioblastomas by providing surgeons with real-time tumor optical contrast. However, visual assessment of PpIX fluorescence is subjective and limited by the distorting effects of light attenuation and tissue autofluorescence. We have previously shown that non-invasive point measurements of absolute PpIX concentration identifies residual tumor that is otherwise non-detectable. Here, we extend this approach to wide-field quantitative fluorescence imaging by implementing spatial frequency domain imaging to recover tissue optical properties across the field-of-view in phantoms and ex vivo tissue.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.