Evidence map›Paper›PMID 26713186›Full record

ArticleBiomedical optics express2015

Semi-automated identification of cones in the human retina using circle Hough transform.

Danuta M Bukowska, Avenell L Chew, Emily Huynh, Irwin Kashani, Sue Ling Wan, Pak Ming Wan, Fred K Chen

Abstract read
In one paragraph

Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Review
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  11. Observational
  12. Article
  13. Review
  14. Fully Automated Estimation of Spacing and Density for Retinal Mosaics.Translational vision science & technology · 2019
    Article
  15. Article
  16. Article
  17. Article
  18. The Reliability of Cone Density Measurements in the Presence of Rods.Translational vision science & technology · 2018
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Danuta M BukowskaCentre for Ophthalmology and Visual Science, The University of Western Australia, 35 Stirling Highway Crawley WA 6009 Perth, Australia ; Lions Eye Institute, 2 Verdun Street, Nedlands WA 6009, Perth, Australia.
Avenell L ChewCentre for Ophthalmology and Visual Science, The University of Western Australia, 35 Stirling Highway Crawley WA 6009 Perth, Australia ; Lions Eye Institute, 2 Verdun Street, Nedlands WA 6009, Perth, Australia.
Emily HuynhLions Eye Institute, 2 Verdun Street, Nedlands WA 6009, Perth, Australia.
Irwin KashaniCentre for Ophthalmology and Visual Science, The University of Western Australia, 35 Stirling Highway Crawley WA 6009 Perth, Australia.
Sue Ling WanCentre for Ophthalmology and Visual Science, The University of Western Australia, 35 Stirling Highway Crawley WA 6009 Perth, Australia ; Lions Eye Institute, 2 Verdun Street, Nedlands WA 6009, Perth, Australia.
Pak Ming WanCentre for Ophthalmology and Visual Science, The University of Western Australia, 35 Stirling Highway Crawley WA 6009 Perth, Australia.
Fred K ChenCentre for Ophthalmology and Visual Science, The University of Western Australia, 35 Stirling Highway Crawley WA 6009 Perth, Australia ; Lions Eye Institute, 2 Verdun Street, Nedlands WA 6009, Perth, Australia ; Department of Ophthalmology, Royal Perth Hospital, 197 Wellington St, WA 6000, Perth, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A large number of human retinal diseases are characterized by a progressive loss of cones, the photoreceptors critical for visual acuity and color perception. Adaptive Optics (AO) imaging presents a potential method to study these cells in vivo. However, AO imaging in ophthalmology is a relatively new phenomenon and quantitative analysis of these images remains difficult and tedious using manual methods. This paper illustrates a novel semi-automated quantitative technique enabling registration of AO images to macular landmarks, cone counting and its radius quantification at specified distances from the foveal center. The new cone counting approach employs the circle Hough transform (cHT) and is compared to automated counting methods, as well as arbitrated manual cone identification. We explore the impact of varying the circle detection parameter on the validity of cHT cone counting and discuss the potential role of using this algorithm in detecting both cones and rods separately.

Indexed as

(100.0100) Image processing(110.1080) Active or adaptive optics(170.3880) Medical and biological imaging(170.4470) Ophthalmology

Identifiers

PMID26713186
PMCPMC4679246

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.