Evidence map›Paper›PMID 26712791›Full record

ArticleToxins2015

Occurrence and Seasonal Variations of Lipophilic Marine Toxins in Commercial Clam Species along the Coast of Jiangsu, China.

Xin-Zhi Wang, Ying Cheng, Na Li, Hong-Mei Wen, Rui Liu, Chen-Xiao Shan, Chuan Chai, Hao Wu

Abstract read
In one paragraph

Article in Toxins, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xin-Zhi WangSchool of Pharmacy, Nanjing University of Chinese Medicines, Xianlin Avenue No. 138, Nanjing 210023, China. wxzatnj@sina.com.
Ying ChengMarine Drug Research and Development Center of Jiangsu Province, Xianlin Avenue No. 138, Nanjing 210023, China. chengyingnj@163.com.
Na LiMarine Drug Research and Development Center of Jiangsu Province, Xianlin Avenue No. 138, Nanjing 210023, China. linna7249@sina.com.
Hong-Mei WenSchool of Pharmacy, Nanjing University of Chinese Medicines, Xianlin Avenue No. 138, Nanjing 210023, China. njwenhm@126.com.
Rui LiuSchool of Pharmacy, Nanjing University of Chinese Medicines, Xianlin Avenue No. 138, Nanjing 210023, China. cpulr@126.com.
Chen-Xiao ShanSchool of Pharmacy, Nanjing University of Chinese Medicines, Xianlin Avenue No. 138, Nanjing 210023, China. thomastiger@163.com.
Chuan ChaiSchool of Pharmacy, Nanjing University of Chinese Medicines, Xianlin Avenue No. 138, Nanjing 210023, China. echo_0523@hotmail.com.
Hao WuSchool of Pharmacy, Nanjing University of Chinese Medicines, Xianlin Avenue No. 138, Nanjing 210023, China. whao5795@vip.sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have examined lipophilic marine toxins (LMTs) in shellfish and toxic algae worldwide, but the occurrence and seasonal variations of LMTs in commercial clams (including Mactra veneriformis, Ruditapes philippinarum, Meretrix meretrix, and Cyclina sinensis) at their major culturing area in Jiangsu, China, remain largely unexplored. In this study, a new solid phase extraction (SPE) in combination with an ultra-fast liquid chromatography and triple-quadrupole linear ion trap mass spectrometry (UFLC-TQ-MS) method was developed to determine the presence of 10 typical LMTs (okadaic acid (OA), yessotoxins (YTXs), azaspiracids (AZA1-3), pectenotoxins (PTX2), gymnodimine (GYM), dinophysistoxins (DTX1&2), and spirolides (SPX1)) in the aforementioned four clam matrices. After confirmation of its sensitivity and precision, this method was used to evaluate the amounts of LMTs in clam samples harvested in five aquaculture zones of the Jiangsu coastal area. Monthly variations of GYM, PTX2, OA, and DTX1&2 in 400 clam samples from the sample areas were determined from January 2014 through August 2015. Peak values were observed during May and August. This is the first systematic report of LMTs detected in clam samples harvested in Jiangsu. Follow-up research and the implementation of protective measures are needed to ensure the safety of clams harvested in this area.

Indexed as

AnimalsBivalviaChinaChromatography, LiquidEnvironmental MonitoringFood ContaminationMarine ToxinsSeasonsTandem Mass SpectrometryMarine ToxinsclamsJiangsu Provincelipophilic marine toxinsseasonal variationsUFLC-TQ-MS

Identifiers

PMID26712791
PMCPMC4728530

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.