Evidence map›Paper›PMID 26712725›Full record

ArticleMolecules (Basel, Switzerland)2015

Benz[c,d]indolium-containing Monomethine Cyanine Dyes: Synthesis and Photophysical Properties.

Eduardo Soriano, Cory Holder, Andrew Levitz, Maged Henary

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

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  10. Introduction of various substitutions to the methine bridge of heptamethine cyanine dyes Via substituted dianil linkers.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Eduardo SorianoDepartment of Chemistry, Georgia State University, 50 Decatur St., Atlanta, GA 30303, USA. esoriano1@gsu.edu.
Cory HolderDepartment of Chemistry, Georgia State University, 50 Decatur St., Atlanta, GA 30303, USA. cholder1@gsu.edu.
Andrew LevitzDepartment of Chemistry, Georgia State University, 50 Decatur St., Atlanta, GA 30303, USA. alevitz1@gsu.edu.
Maged HenaryDepartment of Chemistry, Georgia State University, 50 Decatur St., Atlanta, GA 30303, USA. mhenary1@gsu.edu.
Georgia State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asymmetric monomethine cyanines have been extensively used as probes for nucleic acids among other biological systems. Herein we report the synthesis of seven monomethine cyanine dyes that have been successfully prepared with various heterocyclic moieties such as quinoline, benzoxazole, benzothiazole, dimethyl indole, and benz[e]indole adjoining benz[c,d]indol-1-ium, which was found to directly influence their optical and energy profiles. In this study the optical properties vs. structural changes were investigated using nuclear magnetic resonance and computational approaches. The twisted conformation unique to monomethine cyanines was exploited in DNA binding studies where the newly designed sensor displayed an increase in fluorescence when bound in the DNA grooves compared to the unbound form.

Indexed as

CarbocyaninesComputational BiologyFluorescent DyesMagnetic Resonance SpectroscopyMolecular StructureNucleic AcidsOptical PhenomenaCarbocyaninesFluorescent DyesNucleic Acidscyanine dyeDFT calculationsDNA groovesoptical propertiessynthesisunsymmetrical

Identifiers

PMID26712725
PMCPMC6274575
OpenAlexW2202920218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.