ArticleChinese medical journal2016
Patients Aged 80 Years or Older are Encountered More Potentially Inappropriate Medication Use.
Article in Chinese medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
- Association of changes in medication with the effectiveness of rehabilitation in older patients: a hospital-based observational study.BMC geriatrics · 2026Observational
- Potentially Inappropriate Prescribing to Older Patients Admitted to Units for Integrated Continuous Care: Application of STOPP/START Criteria.Journal of clinical medicine · 2025Article
- Assessment of the potential of drug-drug interactions among population-based oldest-old people in Turkiye.PeerJ · 2025Article
- Frequency of Single or Combined Anticholinergic Medication Usage as Potentially Inappropriate Medications among the Oldest-Old Age Subgroup.Psychiatry and clinical psychopharmacology · 2024Article
- Benzodiazepines in complex biological matrices: Recent updates on pretreatment and detection methods.Journal of pharmaceutical analysis · 2023Review
- Comparison of primary care prescriptions for old and very old hypertensive patients.Turkish journal of medical sciences · 2023Article
- Overuse of medications in low- and middle-income countries: a scoping review.Bulletin of the World Health Organization · 2023Article
- Physicians' Knowledge, Altitudes, and Perceived Barriers of Inappropriate Prescribing for Older Patients in Shanghai, China.Frontiers in pharmacology · 2022Article
- Potentially Inappropriate Medication Among People With Dementia in China: A Nationwide Cross-Sectional Study.Frontiers in pharmacology · 2022Article
- Article
- Geriatric emergency department revisits after discharge with Potentially Inappropriate Medications: A retrospective cohort study.The American journal of emergency medicine · 2021Article
- Potentially inappropriate medication in acute hospitalized elderly patients with polypharmacy: an observational study comparing PRISCUS, STOPP, and Beers criteria.European journal of clinical pharmacology · 2021Observational
- Potentially Inappropriate Prescriptions in Ambulatory Elderly Patients Living in Rural Areas of Romania Using STOPP/START (Version 2) Criteria.Clinical interventions in aging · 2020Article
- Article
- Age-specific differences in non-cardiac comorbidities among elderly patients hospitalized with heart failure: a special focus on young-old, old-old, and oldest-old.Chinese medical journal · 2019Article
- Anticholinergic and sedative medications exposure in older patients: a cross-sectional study.International journal of clinical pharmacy · 2019Article
- Refractory healing after surgical therapy of osteonecrosis of the jaw: associated risk factors in aged patients.Clinical interventions in aging · 2019Article
- Prescription of potentially inappropriate medications among older people with intellectual disability: a register study.BMC pharmacology & toxicology · 2017Article
- Research of Medical Expenditure among Inpatients with Unstable Angina Pectoris in a Single Center.Chinese medical journal · 2017Article
- Research on 2041 Cases of High Inpatient Expenditure and Influence Factors during 3 Years in a Single Center.Chinese medical journal · 2016Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPolypharmacy and potentially inappropriate medications (PIMs) are prominent prescribing issues in elderly patients. This study was to investigate the different prevalence of PIM use in elderly inpatients between 65-79 years of age and 80 years or older, who were discharged from Geriatric Department in West China Hospital.
methodsA large-scale cohort of 1796 inpatients aged 65 years or over was recruited. Respectively, 618 patients were 65-79 years and 1178 patients were 80 years or older. Updated 2012 Beers Criteria by the American Geriatric Society was applied to assess the use of PIM among the investigated samples.
resultsA review of the prescribed medications identified 686 patients aged 80 years or older consumed at least one PIM giving a rate of 58.2%. Conversely, 268 (43.4%) patients aged 65-79 years consumed at least one PIM (χ2 = 40.18, P < 0.001). Patients aged 80 years or older had higher hospitalization expenses, length of stay, co-morbidities, medical prescription, and mortality than patients aged 65-79 years (all with P < 0.001). Patients aged 80 years or older were prescribed with more benzodiazepines, drugs with strong anticholinergic properties, megestrol, antipsychotics, theophylline, and aspirin. In multiple regression analysis, PIM use was significantly associated with female gender, age, number of diagnostic disease, and number of prescribed medication.
conclusionsThe finding from this study revealed that inpatients aged 80 years or older encountered more PIM use than those aged 65-79 years. Anticholinergic properties, megestrol, antipsychotics, theophylline, and aspirin are medications that often prescribed to inpatients aged 80 years or older. Doctors should carefully choose drugs for the elderly, especially the elderly aged 80 years or older.
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