Evidence map›Paper›PMID 26712246›Full record

SynthesisJournal of the American College of Surgeons2016

Evidence for an Antibiotics-First Strategy for Uncomplicated Appendicitis in Adults: A Systematic Review and Gap Analysis.

Anne P Ehlers, David A Talan, Gregory J Moran, David R Flum, Giana H Davidson

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of the American College of Surgeons, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. C-reactive protein and digestive pathologies: A narrative review for daily clinical use.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Readmission after antibiotic management of uncomplicated acute appendicitis in adults: prospective study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Medical Treatment: An Emerging Standard in Acute Appendicitis?Nigerian medical journal : journal of the Nigeria Medical Association
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anne P EhlersDepartment of Surgery, University of Washington, Seattle, WA. Electronic address: apugel@uw.edu.
David A TalanDepartment of Emergency Medicine, Olive View-UCLA Medical Center, Sylmar, CA.
Gregory J MoranDepartment of Emergency Medicine, Olive View-UCLA Medical Center, Sylmar, CA.
David R FlumDepartment of Surgery, University of Washington, Seattle, WA.
Giana H DavidsonDepartment of Surgery, University of Washington, Seattle, WA.

Funding

Renewal: Gastrointestinal Surgery Outcomes Research FellowshipT32DK070555 · NIDDK · UNIVERSITY OF WASHINGTON · PI FLUM, DAVID R · 2010 to 2024
$3.6M
NIDDK NIH HHS T32 DK070555NIDDK NIH HHS T32DK070555
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAnti-Bacterial AgentsAppendectomyAppendicitisHumansTreatment OutcomeAnti-Bacterial Agents

Identifiers

PMID26712246
PMCPMC4769928

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.