Evidence map›Paper›PMID 26711630›Full record

ArticleEuropean journal of epidemiology2016

Incidence of stroke and stroke subtypes in chronic obstructive pulmonary disease.

Martin Söderholm, Malin Inghammar, Bo Hedblad, Arne Egesten, Gunnar Engström

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in European journal of epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Chronic Obstructive Pulmonary Disease and the Risk of Stroke.Annals of the American Thoracic Society · 2017
    Pooled it
  4. Article
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  8. Review
  9. Article
  10. Article
  11. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2022
    Article
  12. Article
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  15. Observational
  16. Article
  17. Lin28 is associated with astrocytic proliferation during intracerebral hemorrhage.International journal of clinical and experimental pathology · 2020
    Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Martin SöderholmCardiovascular Epidemiology Research Group, Department of Clinical Sciences Malmö, Lund University, CRC Building 60, Floor 13, Jan Waldenströms gata 35, 20502, Malmö, Sweden. martin.soderholm@med.lu.se.
Malin InghammarSection for Infection Medicine, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden.
Bo HedbladCardiovascular Epidemiology Research Group, Department of Clinical Sciences Malmö, Lund University, CRC Building 60, Floor 13, Jan Waldenströms gata 35, 20502, Malmö, Sweden.
Arne EgestenSection for Respiratory Medicine, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden.
Gunnar EngströmCardiovascular Epidemiology Research Group, Department of Clinical Sciences Malmö, Lund University, CRC Building 60, Floor 13, Jan Waldenströms gata 35, 20502, Malmö, Sweden.
Lund University · SESkåne University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is uncertain whether the incidence of stroke is increased in patients with chronic obstructive pulmonary disease (COPD), and whether COPD is associated with all subtypes of stroke (i.e. ischemic stroke, intracerebral haemorrhage and subarachnoid haemorrhage). We evaluated the association between COPD and incidence of stroke in a nation-wide cohort study. All individuals between 40 and 84 years of age, hospitalised for COPD between 1987 and 2003 in Sweden were identified in the Swedish hospital discharge register. For each COPD patient (n = 103,419), one reference individual was randomly selected from the general population matched for year of birth, sex and county of residence. After excluding subjects with prior stroke, incidence rates during 10 years follow-up were calculated. Hazard ratios (HR) for stroke comparing COPD patients with reference subjects were estimated using Cox regression adjusting for demographics and comorbidities. Incidence of all-cause stroke (n events = 17,402) was significantly increased in COPD patients compared to reference individuals (HR 1.24, 95 % CI 1.19-1.28), especially during the first 2 years after COPD diagnosis (HR 1.46, 1.37-1.55). Incidences of ischemic stroke (HR 1.20, 1.15-1.25), intracerebral haemorrhage (HR 1.29, 1.16-1.43) and subarachnoid haemorrhage (HR 1.46, 1.16-1.85) were all increased in COPD patients. Incidences of all stroke subtypes are increased in COPD, especially during the first years after COPD diagnosis. The association was independent of several comorbidities, although residual confounding from smoking and hypertension cannot be excluded. A global evaluation of stroke risk factors seems warranted in patients with COPD.

Indexed as

AgedAsthmaCerebral HemorrhageCerebral InfarctionCohort StudiesComorbidityFemaleHumansIncidenceMaleMiddle AgedPulmonary Disease, Chronic ObstructiveRisk FactorsStrokeSwedenCerebral infarctionCOPDIntracerebral haemorrhageStrokeSubarachnoid haemorrhage

Identifiers

PMID26711630
OpenAlexW2208473508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.