Evidence map›Paper›PMID 26711126›Full record

ArticleCurrent infectious disease reports2016

Carbapenem-Resistant Enterobacteriaceae Infections in Children.

Kathleen Chiotos, Jennifer H Han, Pranita D Tamma

Abstract read
In one paragraph

Article in Current infectious disease reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Carbapenem-resistantOpen forum infectious diseases · 2024
    Article
  10. Observational
  11. Investigation of the first reported outbreak of New Delhi metallo-β-lactamase-1-producingAntimicrobial stewardship & healthcare epidemiology : ASHE · 2024
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Colistin use in a carbapenem-resistantSouthern African journal of infectious diseases · 2023
    Article
  17. Article
  18. Article
  19. Genomic Characterization of a Multidrug-ResistantInfection and drug resistance · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kathleen ChiotosDivision of Critical Care, Department of Anesthesia and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. chiotosk@email.chop.edu.
Jennifer H HanDivision of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 811 Blockley Hall, 423 Guardian Drive, Philadelphia, PA, 19104, USA. jennifer.han@uphs.upenn.edu.
Pranita D TammaDivision of Infectious Diseases, Department of Pediatrics, The Johns Hopkins University School of Medicine, 200 North Wolfe Street, Suite 3149, Baltimore, MD, 21287, USA. ptamma1@jhmi.edu.

Funding

Pediatric Hospital Epidemiology and Outcomes Research Training ProgramT32HD060550 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI Christopher Peter Bonafide, John Chris Feudtner · 2010 to 2026
$6.8M
Carbapenem-Resistant Klebsiella Pneumoniae in Long-Term Acute Care HospitalsK01AI103028 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HAN, JENNIFER · 2013 to 2017
$669k
NIAID NIH HHS K01 AI103028NICHD NIH HHS T32 HD060550
6 · The paper itself

Abstract

Carbapenem-resistant Enterobacteriaceae (CRE) are an emerging global public health threat. Infections due to CRE are associated with significant morbidity and mortality. Few therapeutic options are available for treatment of these infections, and optimal antibiotic treatment regimens are unclear. Along with the rapidly increasing prevalence of CRE in the USA and worldwide, several studies have described the epidemiology of CRE in the adult population. While CRE are now also reported sporadically in children, there is a significant lack of data on the epidemiology, risk factors, treatment, and outcomes in this population. This article provides a comprehensive review of what is known to date about CRE, including clinical and molecular epidemiology, microbiologic diagnosis, antibiotic treatment options, and outcomes. In particular, this review will focus on the available data on CRE in the pediatric population.

Indexed as

CarbapenemasesCarbapenem-resistant Enterobacteriaceae (CRE)Gram-negativeKPCsMultidrug-resistant organismsPediatricsResistant gram-negative bacteria

Identifiers

PMID26711126
PMCPMC4975038

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.