ReviewCurrent atherosclerosis reports2016
The Link Between Obstructive Sleep Apnea and Cardiovascular Disease.
Review in Current atherosclerosis reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 6 syntheses or guidelines pooled it, 154 citations in OpenAlex.
- Impacts of renal denervation on blood pressure in patients with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2024Pooled it
- Nocturnal oxygen therapy in obstructive sleep apnoea: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2024Pooled it
- Increased P-wave dispersion in patients with obstructive sleep apnea syndrome: a meta-analysis.Sleep & breathing = Schlaf & Atmung · 2023Pooled it
- Pathway-Specific Polygenic Risk Scores Identify Obstructive Sleep Apnea-Related Pathways Differentially Moderating Genetic Susceptibility to Coronary Artery Disease.Circulation. Genomic and precision medicine · 2022Pooled it
- The effect of obstructive sleep apnea on the increased risk of cardiovascular disease: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Pooled it
- Does continuous positive airway pressure therapy benefit patients with coronary artery disease and obstructive sleep apnea? A systematic review and meta-analysis.Clinical cardiology · 2021Pooled it
- Nocturnal blood pressure and nocturnal blood pressure fluctuations: the effect of short-term CPAP therapy and their association with the severity of obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Trial
- Effect of CPAP therapy on nocturnal blood pressure fluctuations, nocturnal blood pressure, and arterial stiffness in patients with coexisting cardiovascular diseases and obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2021Trial
- Increased platelet activation in sleep apnea subjects with intermittent hypoxemia.Sleep & breathing = Schlaf & Atmung · 2020Trial
- Ambulatory screening tool for sleep apnea: analyzing a single-lead electrocardiogram signal (ECG).Sleep & breathing = Schlaf & Atmung · 2018Trial
- Effect of CPAP, Weight Loss, or CPAP Plus Weight Loss on Central Hemodynamics and Arterial Stiffness.Hypertension (Dallas, Tex. : 1979) · 2017Trial
- Utility of Preoperative Cardiac Workup for Children With Very Severe Obstructive Sleep Apnea.The Laryngoscope · 2026Article
- Metabolomic Biomarkers for Non-Invasive Diagnosis of Coronary Artery Disease and Obstructive Sleep Apnea Co-Occurrence.Nature and science of sleep · 2026Article
- Sleep-disordered breathing subtypes and future diet quality in the Multi-Ethnic Study of Atherosclerosis.Sleep health · 2025Article
- Evaluation of Circulating Levels of ICAM-1 in Obstructive Sleep Apnea (OSA) Adults: Systematic Review, Meta-Analysis, and Trial Sequential Analysis of Link Between OSA and Cardiovascular Disease.Life (Basel, Switzerland) · 2025Review
- Article
- Long sleep duration and good sleep quality reduced incident peptic ulcer disease in a large Taiwanese population follow-up study.International journal of medical sciences · 2025Article
- Article
- From sleep apnea to arrhythmia: p-wave parameters as non-invasive predictors.Frontiers in cardiovascular medicine · 2025Article
- Recent progresses in gut microbiome mediates obstructive sleep apnea-induced cardiovascular diseases.FASEB bioAdvances · 2024Review
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obstructive sleep apnea (OSA) is common in the general population and highly prevalent in patients with cardiovascular disease. In this paper, we review (1) the pathophysiological mechanisms of OSA that may causally contribute to cardiovascular disease; (2) current evidence regarding the association between OSA and hypertension, stroke, ischemic heart disease, heart failure, atrial fibrillation, and cardiovascular mortality; and (3) the impact of continuous positive airway pressure (CPAP) treatment on cardiovascular risk factors and outcomes. We emphasize the importance of obesity as a comorbidity of OSA and a confounder in the association between OSA and cardiovascular disease. We also discuss the importance of addressing obesity in patients with OSA, as a strategy to reduce the burden of cardiovascular risk factors in this population. Implications for the approach of patients' OSA in clinical practice and future research directions are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.