Evidence map›Paper›PMID 26709912›Full record

ReviewPharmacogenetics and genomics2016

PharmGKB summary: very important pharmacogene information for RYR1.

Maria L Alvarellos, Ronald M Krauss, Russell A Wilke, Russ B Altman, Teri E Klein

Abstract readReview
In one paragraph

Review in Pharmacogenetics and genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. The history and future of pharmacogenetics in Aotearoa/New Zealand.Journal of the Royal Society of New Zealand · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Novel Variants in Individuals withFrontiers in neurology · 2018
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria L AlvarellosDepartments of aGenetics bBioengineering, Stanford University, Stanford cChildren's Hospital Oakland Research Institute and UCSF, Oakland, California dDepartment of Medicine, University of North Dakota, Fargo, North Dakota eIMAGENETICS, Sanford Healthcare, Sioux Falls, South Dakota, USA.
Ronald M Krauss
Russell A Wilke
Russ B Altman
Teri E Klein

Funding

PharmGKB: pharmacogenomics knowledge for precision medicineR24GM061374 · NIGMS · STANFORD UNIVERSITY · PI ALTMAN, RUSS BIAGIO, KLEIN, TERI ELLEN · 2010 to 2018
$25.2M
Pharmacogenomics of Statin TherapyP50GM115318 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RISCH, NEIL J. · 2015 to 2019
$14.0M
NIGMS NIH HHS 1P50GM115318-01NIGMS NIH HHS P50 GM115318NIGMS NIH HHS R24 GM061374NIGMS NIH HHS R24 GM61374
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic Predisposition to DiseaseGenetic VariationHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMalignant HyperthermiaMuscle, SkeletalMuscular DiseasesPharmacogeneticsRyanodine Receptor Calcium Release ChannelHydroxymethylglutaryl-CoA Reductase InhibitorsRyanodine Receptor Calcium Release Channel

Identifiers

PMID26709912
PMCPMC4738161

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.