Evidence map›Paper›PMID 26709819›Full record

ArticleCancer2016

Disparities in the use of screening magnetic resonance imaging of the breast in community practice by race, ethnicity, and socioeconomic status.

Jennifer S Haas, Deirdre A Hill, Robert D Wellman, Rebecca A Hubbard, Christoph I Lee, Karen J Wernli, Natasha K Stout, Anna N A Tosteson, Louise M Henderson, Jennifer A Alford-Teaster and 1 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06629896 (Comparison Between Contrast-Enhanced Mammography and Magnetic Resonance Imaging in the Surveillance of High-Risk Women for Breast Cancer), which is not on this map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06629896 narecruitingnot on this mapstarted 2025, after this paper: background citation

Comparison Between Contrast-Enhanced Mammography and Magnetic Resonance Imaging in the Surveillance of High-Risk Women for Breast Cancer: The Randomized Controlled Trial 'Con-trust. Funded by European Commission NextGenerationEU - Ministero Della Salute PNRR: M6/C2_CALL 2023 Full Proposal

TypeinterventionalSponsorAzienda USL Reggio Emilia - IRCCSRan2025 to 2030Enrolled2,200ConditionsBreast Cancer Screening and DiagnosisArmsContrast Enhancement Mammography, magnetic resonance imaging (MRI) and digital mammography (DM)
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
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  13. Sources of Disparities in Surveillance Mammography Performance and Risk-Guided Recommendations for Supplemental Breast Imaging: A Simulation Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
  14. Social Determinants of Health in Imaging-based Cancer Screening: A Case-based Primer with Strategies for Care Improvement.Radiographics : a review publication of the Radiological Society of North America, Inc · 2023
    Article
  15. Article
  16. Brain imaging with portable low-field MRI.Nature reviews bioengineering · 2023
    Article
  17. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Jennifer S HaasDivision of General Internal Medicine and Primary Care, Department of Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Deirdre A HillDepartment of Internal Medicine and Cancer Research Center and School of Medicine, University of New Mexico, Albuquerque, New Mexico.
Robert D WellmanGroup Health Research Institute, Seattle, Washington.
Rebecca A HubbardDepartment of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Christoph I LeeDepartment of Radiology, University of Washington School of Medicine, Seattle, Washington.
Karen J WernliGroup Health Research Institute, Seattle, Washington.
Natasha K StoutDepartment of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, Massachusetts.
Anna N A TostesonDepartment of Medicine, Department of Community and Family Medicine, The Dartmouth Institute, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire.
Louise M HendersonDepartment of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Jennifer A Alford-TeasterDepartment of Medicine, Department of Community and Family Medicine, The Dartmouth Institute, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire.
Tracy L OnegaDepartment of Biomedical Science, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire.
Dartmouth Institute for Health Policy and Clinical Practice · USKaiser Permanente Washington Health Research Institute · USDartmouth College · USHarvard Pilgrim Health Care · USHarvard University · USUniversity of New Mexico · USUniversity of North Carolina at Chapel Hill · USUniversity of Pennsylvania · USUniversity of Washington · US

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
Risk-based Imaging Strategies to Improve Breast Cancer Surveillance OutcomesP01CA154292 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Diana L Miglioretti · 2011 to 2026
$52.9M
Vermont Screening Process Documentation UnitU54CA163303 · NCI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI SPRAGUE, BRIAN L · 2011 to 2017
$6.4M
Promoting personalized decisions for breast cancer screening for women AND theirU54CA163307 · NCI · DARTMOUTH COLLEGE · PI HAAS, JENNIFER S, ONEGA, TRACY · 2011 to 2017
$6.1M
NCI NIH HHS HHSN261201100031CNCI NIH HHS P01 CA154292NCI NIH HHS P30 CA023108NCI NIH HHS U54 CA163303NCI NIH HHS U54 CA163307
6 · The paper itself

Abstract

backgroundUptake of breast magnetic resonance imaging (MRI) coupled with breast cancer risk assessment offers the opportunity to tailor the benefits and harms of screening strategies for women with differing cancer risks. Despite the potential benefits, there is also concern for worsening population-based health disparities.

methodsAmong 316,172 women aged 35 to 69 years from 5 Breast Cancer Surveillance Consortium registries (2007-2012), the authors examined 617,723 negative screening mammograms and 1047 screening MRIs. They examined the relative risks (RRs) of MRI use by women with a <20% lifetime breast cancer risk and RR in the absence of MRI use by women with a ≥20% lifetime risk.

resultsAmong women with a <20% lifetime risk of breast cancer, non-Hispanic white women were found to be 62% more likely than nonwhite women to undergo an MRI (95% confidence interval, 1.32-1.98). Of these women, those with an educational level of some college or technical school were 43% more likely and those who had at least a college degree were 132% more likely to receive an MRI compared with those with a high school education or less. Among women with a ≥20% lifetime risk, there was no statistically significant difference noted with regard to the use of screening MRI by race or ethnicity, but high-risk women with a high school education or less were less likely to undergo screening MRI than women who had graduated from college (RR, 0.40; 95% confidence interval, 0.25-0.63).

conclusionsUptake of screening MRI of the breast into clinical practice has the potential to worsen population-based health disparities. Policies beyond health insurance coverage should ensure that the use of this screening modality reflects evidence-based guidelines.

Indexed as

RegistriesSocial ClassAdultAgedBlack or African AmericanBreastBreast NeoplasmsEarly Detection of CancerEducational StatusEthnicityEvidence-Based MedicineFemaleHealthcare DisparitiesHispanic or LatinoHumansMagnetic Resonance Imagingbreast cancer screeningguidelineshealth disparitiesprimary care

Identifiers

PMID26709819
PMCPMC4742376
OpenAlexW2207721691

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.