Evidence map›Paper›PMID 26709471›Full record

ReviewCurrent opinion in lipidology2016

High-density lipoprotein function in rheumatoid arthritis.

Michelle J Ormseth, C Michael Stein

Abstract readReview
In one paragraph

Review in Current opinion in lipidology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Exercise is Associated With Increased Small HDL Particle Concentration and Decreased Vascular Stiffness in Rheumatoid Arthritis.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2018
    Article
  10. The effects of conventional drugs in the treatment of rheumatoid arthritis on the serum lipids.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michelle J OrmsethVanderbilt University Medical Center, Nashville, Tennessee, USA.
C Michael Stein
Vanderbilt University Medical Center · US

Funding

Non-coding RNA & Bioinformatics CoreP01HL116263 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI VICKERS, KASEY C · 2014 to 2025
$24.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)KL2TR000446 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$2.8M
Functional Impact of HDL transport of miRNA in rheumatoid arthritisK23AR068443 · NIAMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ORMSETH, MICHELLE JANE · 2015 to 2016
$184k
Annual International Science of Team Science ConferenceR13TR000046 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CONTRACTOR, NOSHIR S · 2012 to 2015
$40k
NCATS NIH HHS KL2 TR000446NCATS NIH HHS KL2 TR00046NCATS NIH HHS R13 TR000046NHLBI NIH HHS P01 HL116263NIAMS NIH HHS K23 AR068443
6 · The paper itself

Abstract

purpose of reviewPatients with rheumatoid arthritis (RA) have accelerated atherosclerosis despite the appearance of having a less atherogenic lipid profile; however, lipoprotein function rather than concentration may be a better indicator of atherosclerotic risk. The purpose of this review is to summarize recent findings concerning HDL function in patients with RA. RECENT

findingsTwo major activities of HDL, its antioxidant and cholesterol efflux functions have been examined in RA. HDL antioxidant capacity is inversely associated with inflammation and RA disease activity; however, there is no clear consensus if antioxidant capacity is altered significantly in RA compared with control study participants. Moreover, despite numerous studies there is no consensus whether HDL cholesterol efflux capacity is significantly altered in RA compared with control study participants or influenced by inflammation or disease activity. SUMMARY: Additional studies will be valuable to consolidate existing data and find consensus. Moreover, studies evaluating the impact of various HDL functions on cardiovascular disease in RA are needed.

Indexed as

AnimalsAntioxidantsArthritis, RheumatoidCholesterol, HDLHumansLipoproteins, HDLAntioxidantsCholesterol, HDLLipoproteins, HDL

Identifiers

PMID26709471
PMCPMC4703526
OpenAlexW2197302719

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.