Evidence map›Paper›PMID 26709385›Full record

ArticleTechnology2015

Scaffold-integrated microchips for end-to-end

Jungwoo Lee, Nathaniel Kohl, Sachin Shanbhang, Biju Parekkadan

Abstract read
In one paragraph

Article in Technology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Targeted Cancer Therapy-on-A-Chip.Advanced healthcare materials · 2024
    Review
  3. The Applications and Challenges of the Development ofCellular and molecular bioengineering · 2023
    Review
  4. Review
  5. Engineering the pre-metastatic niche.Nature biomedical engineering · 2017
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jungwoo LeeCenter for Engineering in Medicine, Massachusetts General Hospital & Harvard Medical School and Shriners Hospital for Children, Boston, MA 02114, USA ; Department of Chemical Engineering, University of Massachusetts, Amherst, MA 01003, USA.
Nathaniel KohlDepartment of Scientific Computing, Florida State University, Tallahassee, FL 32306, USA.
Sachin ShanbhangDepartment of Scientific Computing, Florida State University, Tallahassee, FL 32306, USA.
Biju ParekkadanCenter for Engineering in Medicine, Massachusetts General Hospital & Harvard Medical School and Shriners Hospital for Children, Boston, MA 02114, USA ; Harvard Stem Cell Institute, Boston, MA 02138, USA.

Funding

Artificial, Humanized Stem Cell NichesR01EB012521 · NIBIB · RUTGERS, THE STATE UNIV OF N.J. · PI PAREKKADAN, BIJU · 2011 to 2021
$6.0M
Elucidating Essential Components of Bone Marrow MetastasisR00CA163671 · NCI · UNIVERSITY OF MASSACHUSETTS AMHERST · PI LEE, JUNGWOO · 2014 to 2016
$740k
Peripheral Tissue Antigen Display by Mesenchymal Stem CellsK01DK087770 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI PAREKKADAN, BIJU · 2010 to 2014
$682k
Elucidating Essential Components of Bone Marrow MetastasisK99CA163671 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, JUNGWOO · 2012 to 2013
$179k
NCI NIH HHS K99 CA163671NCI NIH HHS R00 CA163671NIBIB NIH HHS R01 EB012521NIDDK NIH HHS K01 DK087770
6 · The paper itself

Abstract

Microfluidic technologies have substantially advanced cancer research by enabling the isolation of rare circulating tumor cells (CTCs) for diagnostic and prognostic purposes. The characterization of isolated CTCs has been limited due to the difficulty in recovering and growing isolated cells with high fidelity. Here, we present a strategy that uses a 3D scaffold, integrated into a microfludic device, as a transferable substrate that can be readily isolated after device operation for serial use

Identifiers

PMID26709385
PMCPMC4687757

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.