Evidence map›Paper›PMID 26709356›Full record

ArticleCurrent bladder dysfunction reports2014

Future Perspectives in Bladder Tissue Engineering.

Bradley C Gill, Margot S Damaser, Christopher J Chermansky

Abstract read
In one paragraph

Article in Current bladder dysfunction reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Engineering molecular imaging strategies for regenerative medicine.Bioengineering & translational medicine · 2018
    Review
  4. Folding artificial mucosa with cell-laden hydrogels guided by mechanics models.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  5. Review
  6. Review
  7. The Management of the Pediatric Neurogenic Bladder.Current bladder dysfunction reports
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bradley C GillDepartment of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic ; Lerner College of Medicine, Education Institute, Cleveland Clinic ; Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic.
Margot S DamaserDepartment of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic ; Lerner College of Medicine, Education Institute, Cleveland Clinic ; Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic ; Advanced Platform Technology Center, Cleveland Veterans Affairs Medical Center.
Christopher J ChermanskyDepartment of Urology, University of Pittsburgh Medical Center.
Cleveland Clinic · USUniversity of Pittsburgh Medical Center · US

Funding

Stem Cell Homing for Treatment of Female Pelvic Floor DisordersR01HD059859 · NICHD · CLEVELAND CLINIC LERNER COM-CWRU · PI DAMASER, MARGOT S. · 2010 to 2014
$1.6M
Regenerative Therapy for Pelvic Organ ProlapseR21HD078820 · NICHD · CLEVELAND CLINIC LERNER COM-CWRU · PI DAMASER, MARGOT S., RAMAMURTHI, ANAND · 2014 to 2015
$431k
NICHD NIH HHS R01 HD059859NICHD NIH HHS R21 HD078820ORD VA F9261-LRRD VA I01 RX000228
6 · The paper itself

Abstract

Substantial clinical need persists for improved autologous tissues to augment or replace the urinary bladder and research has begun to address this using tissue engineering techniques. The implantation of both tissue scaffolds which allow for native bladder tissue ingrowth and autologous bladder grafts created from in vitro cellularization of such scaffolds have been tested clinically; however, successful outcomes in both scenarios have been challenged by insufficient vascularity resulting from large graft sizes, which subsequently limits tissue ingrowth and leads to central graft ischemia. Consequently, recent research has focused on developing better methods to produce scaffolds with increased tissue ingrowth and vascularity. This review provides an update on bladder tissue engineering and outlines the challenges that remain to clinical implementation.

Indexed as

Autologous GraftRegenerative UrologyStem CellsTissue EngineeringUrinary Bladder

Identifiers

PMID26709356
PMCPMC4689598
OpenAlexW2178524609

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.