ArticleThe Kaohsiung journal of medical sciences2015
The relation of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume with the presence and severity of Behçet's syndrome.
Article in The Kaohsiung journal of medical sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
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Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 111 citations in OpenAlex.
- Role of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as potential biomarkers in Behçet's disease: a meta-analysis.Zeitschrift fur Rheumatologie · 2024Pooled it
- Neutrophil to Lymphocyte Ratio in Epilepsy: A Systematic Review.Mediators of inflammation · 2022Pooled it
- Recent Advances in Camel Immunology.Frontiers in immunology · 2020Pooled it
- The Role of HLA-B Typing in Behçet's Disease and Spondyloarthritis: Genetic and Clinical Insights.Life (Basel, Switzerland) · 2026Article
- Pan-Immune-Inflammation Value Predicts Disease Activity and Ocular Involvement in Behçet's Disease: A Case-Control Study.Mediterranean journal of rheumatology · 2026Article
- Is the C reactive protein/albumin ratio a good tool for retinal vein occlusion?BMC ophthalmology · 2025Article
- Inflammatory hematological ratios and subclinical microvascular changes of fundus in Behçet disease.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- The Role of Neutrophil to Lymphocytes Ratio (NLR) as a Predictor of Disease Activity in Behcet's Syndrome-A Comprehensive Review.Journal of clinical medicine · 2025Review
- Hematological ratios, immune-related adverse events and mortality in patients treated with immune checkpoint inhibitors.PloS one · 2025Article
- Decreased Neutrophil-to-lymphocyte Ratio in Patients with Vitiligo: National Data Analysis.Acta dermato-venereologica · 2024Article
- Increased Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in Chronic and Severe Urticaria.Acta dermato-venereologica · 2024Article
- Evaluation of the hematological inflammatory parameters in the patients with immune thrombocytopenic purpura: A case-control study.Health science reports · 2024Article
- Article
- A potential biomarker of disease activity in systemic lupus erythematosus, systemic immune-inflammation index.Northern clinics of Istanbul · 2024Article
- Elevated hematologic ratios are correlated with acne severity: a national, retrospective cohort study.Frontiers in medicine · 2024Article
- Inflammatory and Nutritional Markers as Indicators for Diagnosing and Assessing Disease Activity in MS and NMOSD.Journal of inflammation research · 2024Article
- Article
- Association of Neutrophil Lymphocyte Ratio and Platelet Lymphocyte Ratio with Persistent Allergic Rhinitis.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Importance of hematological markers in familial Mediterranean fever in terms of disease severity and amyloidosis.Rheumatology international · 2023Article
- Role of Neutrophil-to-Lymphocyte Ratio (NLR) in Patients with Mycosis Fungoides.Diagnostics (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Behçet's syndrome (BS) is associated with chronic inflammation and endothelial dysfunction. Although there have been extensive investigations on neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and mean platelet volume (MPV) in many diseases, their roles in BS is unclear. The purpose of the present study was to evaluate NLR, PLR, and MPV levels in BS patients and explore their clinical significance. The study included 254 patients with BS and 173 healthy individuals. Age, sex, age of onset, duration of disease, smoking, Behçet activity score, total white blood counts, neutrophil, platelet, and T lymphocyte counts of the patients were recorded. White blood cell (WBC), neutrophil, platelet, NLR, and PLR were significantly higher in patients with BS when compared with healthy controls (all p < 0.001). Lymphocyte counts and MPVs of the BS group were not statistically different from healthy controls (all p > 0.05). In the BS group, PLR and MPV were significantly different among the three severity groups (p = 0.037 and p = 0.016, respectively). We showed that any laboratory markers were not associated with joint, eye, central nervous system, large vessel, or gastrointestinal involvement in BS. NLR was shown to be an independent factor for BS by multivariate analysis. We suggest that NLR can be considered to be a diagnostic criterion of BS given the support of the findings from larger prospective studies.
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