ArticleExperimental & applied acarology2016
Acaricidal activity of Asarum heterotropoides root-derived compounds and hydrodistillate constitutes toward Dermanyssus gallinae (Mesostigmata: Dermanyssidae).
Article in Experimental & applied acarology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 26 citations in OpenAlex.
- Natural Products as Mite Control Agents in Animals: A Review.Molecules (Basel, Switzerland) · 2023Review
- Evaluation of the Acaricidal Effectiveness of Fipronil and Phoxim in Field Populations ofVeterinary sciences · 2022Article
- Acaricidal Activity of Annonaceae Plants for Dermanyssus gallinae (Acari: Dermanyssidae) and Metabolomic Profile by HPLC-MS/MS.Neotropical entomology · 2021Article
- Pharmacokinetic Study of Safrole and Methyl Eugenol after Oral Administration of the Essential Oil Extracts ofBioMed research international · 2021Article
- Fumigant Toxicity and Oviposition Deterrent Activity of Volatile Constituents from Asari Radix et Rhizoma against Phthorimaea operculella (Lepidoptera: Gelechiidae).Journal of insect science (Online) · 2020Article
- Integrative transcriptomics and metabolomics analyses provide hepatotoxicity mechanisms of asarum.Experimental and therapeutic medicine · 2020Article
- Toxicity and effects of essential oils and their components on Dermanyssus gallinae (Acari: Dermanyssidae).Experimental & applied acarology · 2019Article
- Toxic and Repellent Effects of Volatile Phenylpropenes fromMolecules (Basel, Switzerland) · 2018Article
- Acaricidal and repellent effects of Cnidium officinale-derived material against Dermanyssus gallinae (Acari: Dermanyssidae).Experimental & applied acarology · 2018Article
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6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The acaricidal activity of Asarum heterotropoides root-derived principles, methyleugenol, safrole, 3-carene, α-asarone, pentadecane and A. heterotropoides root steam distillate constituents was tested against poultry red mites Dermanyssus gallinae (De Geer). All active principles were identified by spectroscopic analysis. Results were compared with those of two conventional acaricides, benzyl benzoate and N,N-diethyl-3-methylbenzamide (DEET). Methyleugenol (24 h LC50 = 0.57 µg/cm(2)) and safrole (24 h LC50 = 8.54 µg/cm(2)) were the most toxic compounds toward D. gallinae, followed by 3,4,5-trimethoxytoluene, 3,5-dimethoxytoluene, estragole, α-terpineol, verbenone, eucarvone, linalool, and terpinen-4-ol (LC50 = 15.65-27.88 µg/cm(2)). Methyleugenol was 16.7× and 11.0× more toxic than benzyl benzoate (LC50 = 9.52 μg/cm(2)) and DEET (LC50 = 6.28 μg/cm(2)), respectively; safrole was 1.1× and 0.73× more toxic. Asarum heterotropoides root-derived materials, particularly methyleugenol and safrole, merit further study as potential acaricides. Global efforts to reduce the level of highly toxic synthetic acaricides in indoor environments justify further studies on A. heterotropoides root extract and steam distillate preparations containing the active constituents described as potential contact-action fumigants for the control of mites.
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