Evidence map›Paper›PMID 26708015›Full record

ArticleTrends in neurosciences2016

A Spinal Circuit for Mechanically-Evoked Itch.

Steve Davidson

Abstract readComment
PubMed Publisher
In one paragraph

Article in Trends in neurosciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Steve DavidsonPain Research Center, Department of Anesthesiology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA. Electronic address: steve.davidson@uc.edu.

Funding

Functional Characterization and Sensitization of Human PruriceptorsR21AR068012 · NIAMS · UNIVERSITY OF CINCINNATI · PI DAVIDSON, STEVE · 2016 to 2017
$389k
NIAMS NIH HHS R21 AR068012
6 · The paper itself

Abstract

A satisfactory neurobiological understanding of itch has proved difficult to reach. Bourane et al. have now uncovered a previously unrecognized spinal circuit for mechanically-induced itch and elucidated a mechanism that keeps it in check. Dysregulation of this circuit could contribute to chronic itch, suggesting a new strategy for itch relief.

Indexed as

Neural InhibitionSynaptic TransmissionAnimalsInterneuronsMechanotransduction, CellularPruritusSpinal CordItchmechanoreceptorpainscratchspinaltouch

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.