ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
Aerobic capacity and health-related quality of life in adults HIV-infected patients with and without lipodystrophy.
Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Chronotropic Incompetence Among People With HIV Improves With Exercise Training in the Exercise for Healthy Aging Study.The Journal of infectious diseases · 2024Trial
- Perceptions and management of diabetes and obesity among people living with HIV in Côte d'Ivoire: a qualitative study.BMC public health · 2025Article
- Impact of Body Mass Index and VO2 Max on Symptoms, Physical Activity, and Physical Function in a Multinational Sample of People with HIV.AIDS and behavior · 2025Article
- Efficacy of aerobic exercise for HIV-associated neurocognitive disorders receiving ART: An RCT.The South African journal of physiotherapy · 2024Article
- Chronotropic Incompetence among People with HIV Improves with Exercise Training in the Exercise for Healthy Aging Study.medRxiv : the preprint server for health sciences · 2023Article
- Association of SARS-CoV-2 Infection and Cardiopulmonary Long COVID With Exercise Capacity and Chronotropic Incompetence Among People With HIV.Journal of the American Heart Association · 2023Article
- Comparison of functioning and health-related quality of life among patients with HTLV-1, HIV, and HIV-HTLV-1-coinfection.Revista da Sociedade Brasileira de Medicina Tropical · 2021Article
- Brief Report: Effects of Low-Volume High-Intensity Interval Training in Hispanic HIV+ Women: A Nonrandomized Study.Journal of acquired immune deficiency syndromes (1999) · 2020Article
- Physical activity levels among Malawian adults living with HIV and receiving anti-retroviral therapy.Malawi medical journal : the journal of Medical Association of Malawi · 2020Article
- Evaluating the Effectiveness of Physical Exercise Interventions in Persons Living With HIV: Overview of Systematic Reviews.AIDS education and prevention : official publication of the International Society for AIDS Education · 2017Review
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4 authors at 1 institution in 1 country.
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Abstract
introductionHIV infection and its therapy which can affect their aerobic capacity and health-related quality of life of patients.
objectiveWe conducted a cross-sectional study to determine if aerobic capacity and health related quality of life was decreased in HIV-infected patients receiving highly active antiretroviral therapy and comparing patients with and without lipodystrophy. RESEARCH DESIGN AND
methodsHIV-infected patients older than 18 years, and in current use of highly active antiretroviral therapy drugs, were evaluated for blood count, fasting total cholesterol, high density lipoprotein, triglycerides, glucose, HIV viral load and CD4/CD8 counts, body composition, peak oxygen consumption (peak VO2) and metabolic equivalent. Health related quality of life was assessed by using Short Form-36 (SF-36). Statistical analysis was carried out using SPSS version 20.0.
resultsA total of 63 patients with mean age of 43.1±6.4 years were evaluated, of these 34 (54%) had lipodystrophy. The average peak VO2 (31.4±7.6mLkg(-1)min(-1)) was significantly lower (p<0.01) than expected values (37.9±5.6mLkg(-1)min(-1)) according to the characteristics of the patients. The lipodystrophy group presented with a significant difference in muscle mass, body fat, peak VO2 and metabolic equivalent and in functional capacity domains of SF-36.
conclusionAerobic capacity values were reduced in HIV-infected patients under highly active antiretroviral therapy when compared to predicted values. Lipodystrophy was associated with reduced aerobic capacity and higher frequency of metabolic syndrome. Lifestyle modification should be a priority in the management of chronic HIV disease.
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