Evidence map›Paper›PMID 26707449›Full record

ArticleJournal of biomedical informatics2016

Classification of hospital acquired complications using temporal clinical information from a large electronic health record.

Jeremy L Warner, Peijin Zhang, Jenny Liu, Gil Alterovitz

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. In-hospital complications in an acute care geriatric unitBiomedica : revista del Instituto Nacional de Salud · 2021
    Observational
  5. Article
  6. Economic evaluations of big data analytics for clinical decision-making: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2020
    Article
  7. Article
  8. Article
  9. Temporal biomedical data analytics.Journal of biomedical informatics · 2019
    Article
  10. Article
  11. Careflow Mining Techniques to Explore Type 2 Diabetes Evolution.Journal of diabetes science and technology · 2018
    Article
  12. A web-based data visualization tool for the MIMIC-II database.BMC medical informatics and decision making · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeremy L WarnerDepartment of Medicine, Division of Hematology & Oncology, Vanderbilt University, Nashville, TN, USA; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA. Electronic address: jeremy.warner@vanderbilt.edu.
Peijin ZhangSchool of Computer Science, Carnegie Mellon University, Pittsburgh, PA, USA.
Jenny LiuDepartment of Electrical Engineering & Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
Gil AlterovitzDepartment of Electrical Engineering & Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA; Center for Biomedical Informatics, Harvard Medical School, Boston, MA, USA; Children's Hospital Informatics Program at Harvard-MIT Health Sciences & Technology, Boston, MA, USA.

Funding

A Holistic Approach to Information Processing for Biomedical NetworksR00LM009826 · NLM · BOSTON CHILDREN'S HOSPITAL · PI ALTEROVITZ, GIL · 2010 to 2012
$727k
NLM NIH HHS 4R00LM009826-NLM NIH HHS R00 LM009826
6 · The paper itself

Abstract

Hospital acquired complications (HACs) are serious problems affecting modern day healthcare institutions. It is estimated that HACs result in an approximately 10% increase in total inpatient hospital costs across US hospitals. With US hospital spending totaling nearly $900 billion per annum, the damages caused by HACs are no small matter. Early detection and prevention of HACs could greatly reduce strains on the US healthcare system and improve patient morbidity & mortality rates. Here, we describe a machine-learning model for predicting the occurrence of HACs within five distinct categories using temporal clinical data. Using our approach, we find that at least $10 billion of excessive hospital costs could be saved in the US alone, with the institution of effective preventive measures. In addition, we also identify several keystone features that demonstrate high predictive power for HACs over different time periods following patient admission. The classifiers and features analyzed in this study show high promise of being able to be used for accurate prediction of HACs in clinical settings, and furthermore provide novel insights into the contribution of various clinical factors to the risk of developing HACs as a function of healthcare system exposure.

Indexed as

Clinical CodingCross InfectionElectronic Health RecordsHospitalizationHumansMedical InformaticsPostoperative ComplicationsClassificationElectronic health recordHospital acquired complicationsRankingTemporal

Identifiers

PMID26707449
PMCPMC4792687

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.