ArticleThe international journal of cardiovascular imaging2016
Correlation of CT-based regional cardiac function (SQUEEZ) with myocardial strain calculated from tagged MRI: an experimental study.
Article in The international journal of cardiovascular imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Clinical application of cardiac computed tomography in cardiomyopathy.The international journal of cardiovascular imaging · 2026Review
- Deep learning enables fully automated cineCT-based assessment of regional right ventricular function.European heart journal. Imaging methods and practice · 2026Article
- Image-Guided Cardiac Regeneration via a 3D Bioprinted Vascular Patch with Built-in CT Visibility.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2025Article
- Successful cardiac resynchronization therapy reduces negative septal work in patient-specific models of dyssynchronous heart failure.PLoS computational biology · 2024Article
- 3D regional evaluation of right ventricular myocardial work from cineCT.medRxiv : the preprint server for health sciences · 2024Article
- Successful Cardiac Resynchronization Therapy Reduces Negative Septal Work in Patient-Specific Models of Dyssynchronous Heart Failure.bioRxiv : the preprint server for biology · 2024Article
- Myocardial Regional Shortening from 4D Cardiac CT Angiography for the Detection of Left Ventricular Segmental Wall Motion Abnormality.Radiology. Cardiothoracic imaging · 2023Article
- DiFiR-CT: Distance field representation to resolve motion artifacts in computed tomography.Medical physics · 2023Article
- Gender Medicine in Clinical Radiology Practice.Journal of personalized medicine · 2023Review
- Regional left ventricular endocardial strains estimated from low-dose 4DCT: Comparison with cardiac magnetic resonance feature tracking.Medical physics · 2022Article
- Four-dimensional computed tomography of the left ventricle, Part I: Motion artifact reduction.Medical physics · 2022Article
- Detection of left ventricular wall motion abnormalities from volume rendering of 4DCT cardiac angiograms using deep learning.Frontiers in cardiovascular medicine · 2022Article
- Deep learning automates detection of wall motion abnormalitiesFrontiers in cardiovascular medicine · 2022Article
- Octree Representation Improves Data Fidelity of Cardiac CT Images and Convolutional Neural Network Semantic Segmentation of Left Atrial and Ventricular Chambers.Radiology. Artificial intelligence · 2021Article
- Optimisation of Left Atrial Feature Tracking Using Retrospective Gated Computed Tomography Images.Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH (Conference) · 2021Article
- Hyperparameter optimisation and validation of registration algorithms for measuring regional ventricular deformation using retrospective gated computed tomography images.Scientific reports · 2021Article
- Novel 4DCT Method to Measure Regional Left Ventricular Endocardial Shortening Before and After Transcatheter Mitral Valve Implantation.Structural heart : the journal of the Heart Team · 2021Article
- Automated 4-dimensional regional myocardial strain evaluation using cardiac computed tomography.The international journal of cardiovascular imaging · 2020Article
- Low-Radiation-Dose Stress Myocardial Perfusion Measurement Using First-Pass Analysis Dynamic Computed Tomography: A Preliminary Investigation in a Swine Model.Investigative radiology · 2019Article
- Anthropomorphic left ventricular mesh phantom: a framework to investigate the accuracy of SQUEEZ using Coherent Point Drift for the detection of regional wall motion abnormalities.Journal of medical imaging (Bellingham, Wash.) · 2019Article
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5 authors.
Funding
Abstract
The objective of this study was to investigate the correlation between local myocardial function estimates from CT and myocardial strain from tagged MRI in the same heart. Accurate detection of regional myocardial dysfunction can be an important finding in the diagnosis of functionally significant coronary artery disease. Tagged MRI is currently a reference standard for noninvasive regional myocardial function analysis; however, it has practical drawbacks. We have developed a CT imaging protocol and automated image analysis algorithm for estimating regional cardiac function from a few heartbeats. This method tracks the motion of the left ventricular (LV) endocardial surface to produce local function maps: we call the method Stretch Quantification of Endocardial Engraved Zones (SQUEEZ). Myocardial infarction was created by ligation of the left anterior descending coronary artery for 2 h followed by reperfusion in canine models. Tagged and cine MRI scans were performed during the reperfusion phase and first-pass contrast enhanced CT scans were acquired. The average delay between the CT and MRI scans was <1 h. Circumferential myocardial strain (Ecc) was calculated from the tagged MRI data. The agreement between peak systolic Ecc and SQUEEZ was investigated in 162 segments in the 9 hearts. Linear regression and Bland-Altman analysis was used to assess the correlation between the two metrics of local LV function. The results show good agreement between SQUEEZ and Ecc: (r = 0.71, slope = 0.78, p < 0.001). Furthermore, Bland-Altman showed a small bias of -0.02 with 95 % confidence interval of 0.1, and standard deviation of 0.05 representing ~6.5 % of the dynamic range of LV function. The good agreement between the estimates of local myocardial function obtained from CT SQUEEZ and tagged MRI provides encouragement to investigate the use of SQUEEZ for measuring regional cardiac function at a low clinical dose in humans.
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