Evidence map›Paper›PMID 26706819›Full record

ArticleMicrobes and infection2016

Burden and viral aetiology of influenza-like illness and acute respiratory infection in intensive care units.

Fabio Tramuto, Carmelo Massimo Maida, Giuseppe Napoli, Caterina Mammina, Alessandra Casuccio, Cinzia Cala', Emanuele Amodio, Francesco Vitale

Abstract read
In one paragraph

Article in Microbes and infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Article
  4. Article
  5. Review
  6. Observational
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fabio TramutoDepartment of Health Promotion Sciences and Mother-Child Care "G. D'Alessandro" - Hygiene Section, University of Palermo, Palermo, Italy; Clinical Epidemiology Unit, University Hospital "Paolo Giaccone", Palermo, Italy. Electronic address: fabio.tramuto@unipa.it.
Carmelo Massimo MaidaDepartment of Health Promotion Sciences and Mother-Child Care "G. D'Alessandro" - Hygiene Section, University of Palermo, Palermo, Italy. Electronic address: carmelo.maida@unipa.it.
Giuseppe NapoliDepartment of Health Promotion Sciences and Mother-Child Care "G. D'Alessandro" - Hygiene Section, University of Palermo, Palermo, Italy. Electronic address: g.napoli15@virgilio.it.
Caterina MamminaDepartment of Health Promotion Sciences and Mother-Child Care "G. D'Alessandro" - Hygiene Section, University of Palermo, Palermo, Italy; Clinical Epidemiology Unit, University Hospital "Paolo Giaccone", Palermo, Italy. Electronic address: caterina.mammina@unipa.it.
Alessandra CasuccioDepartment of Health Promotion Sciences and Mother-Child Care "G. D'Alessandro" - Hygiene Section, University of Palermo, Palermo, Italy. Electronic address: alessandra.casuccio@unipa.it.
Cinzia Cala'Department of Health Promotion Sciences and Mother-Child Care "G. D'Alessandro" - Hygiene Section, University of Palermo, Palermo, Italy. Electronic address: cinzia.cala@unipa.it.
Emanuele AmodioDepartment of Health Promotion Sciences and Mother-Child Care "G. D'Alessandro" - Hygiene Section, University of Palermo, Palermo, Italy. Electronic address: amoema79@libero.it.
Francesco VitaleDepartment of Health Promotion Sciences and Mother-Child Care "G. D'Alessandro" - Hygiene Section, University of Palermo, Palermo, Italy; Clinical Epidemiology Unit, University Hospital "Paolo Giaccone", Palermo, Italy. Electronic address: francesco.vitale@unipa.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this investigation was to study the viral aetiology of influenza-like illness (ILI) and acute respiratory tract infection (ARTI) among patients requiring intensive care unit admission. A cross-sectional retrospective study was carried out in Sicily over a 4-year period. A total of 233 respiratory samples of patients with ILI/ARTI admitted to intensive care units were molecularly analyzed for the detection of a comprehensive panel of aetiologic agents of viral respiratory infections. About 45% of patients was positive for at least one pathogen. Single aetiology occurred in 75.2% of infected patients, while polymicrobial infection was found in 24.8% of positive subjects. Influenza was the most common aetiologic agent (55.7%), especially among adults. Most of patients with multiple aetiology (76.9%) were adults and elderly. Mortality rates among patients with negative or positive aetiology did not significantly differ (52.4% and 47.6%, respectively). Highly transmissible respiratory pathogens are frequently detected among patients with ILI/ARTI admitted in intensive care units, showing the occurrence of concurrent infections by different viruses. The knowledge of the circulation of several types of microorganisms is of crucial importance in terms of appropriateness of therapies, but also for the implication in prevention strategies and hospital epidemiology.

Indexed as

AdolescentAdultAged, 80 and overAge FactorsChildChild, PreschoolCoinfectionCross-Sectional StudiesFemaleHumansInfantInfant, NewbornIntensive Care UnitsMaleMiddle AgedRespiratory Tract InfectionsCo-infectionInfluenza-like illnessIntensive care unitsItalySicilyViral infection

Identifiers

PMID26706819
PMCPMC7129629

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.