Evidence map›Paper›PMID 26706667›Full record

Trial reportContemporary clinical trials2016

A culturally-tailored behavioral intervention trial for alcohol use disorders in three American Indian communities: Rationale, design, and methods.

Michael G McDonell, Jenny R Nepom, Emily Leickly, Astrid Suchy-Dicey, Kait Hirchak, Abigail Echo-Hawk, Stephen M Schwartz, Darren Calhoun, Dennis Donovan, John Roll and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Contemporary clinical trials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Michael G McDonellPartnerships for Native Health, Department of Epidemiology, University of Washington, 1100 Olive Way, Suite 1200, Box 357236, Seattle, WA 98101, USA; Elson S Floyd College of Medicine, Washington State University, USA.
Jenny R NepomPartnerships for Native Health, Department of Epidemiology, University of Washington, 1100 Olive Way, Suite 1200, Box 357236, Seattle, WA 98101, USA.
Emily LeicklyPartnerships for Native Health, Department of Epidemiology, University of Washington, 1100 Olive Way, Suite 1200, Box 357236, Seattle, WA 98101, USA.
Astrid Suchy-DiceyPartnerships for Native Health, Department of Epidemiology, University of Washington, 1100 Olive Way, Suite 1200, Box 357236, Seattle, WA 98101, USA.
Kait HirchakDepartment of Health Policy and Administration, Washington State University, Spokane, WA 99210-1495, USA.
Abigail Echo-HawkPartnerships for Native Health, Department of Epidemiology, University of Washington, 1100 Olive Way, Suite 1200, Box 357236, Seattle, WA 98101, USA.
Stephen M SchwartzPartnerships for Native Health, Department of Epidemiology, University of Washington, 1100 Olive Way, Suite 1200, Box 357236, Seattle, WA 98101, USA; Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, Seattle, WA 98109-1024, USA.
Darren CalhounMed Star Health Research Institute, 1616 E. Indian School Rd., Phoenix, AZ 85016, USA.
Dennis DonovanDepartment of Psychiatry and Behavioral Sciences, University of Washington, 325 Ninth Ave, Box 359911, Seattle, WA 98195, USA.
John RollWashington State University, Spokane, WA 99210-1495, USA.
Richard RiesDepartment of Psychiatry and Behavioral Sciences, University of Washington, 325 Ninth Ave, Box 359911, Seattle, WA 98195, USA.
Dedra BuchwaldPartnerships for Native Health, Department of Epidemiology, University of Washington, 1100 Olive Way, Suite 1200, Box 357236, Seattle, WA 98101, USA; Elson S Floyd College of Medicine, Washington State University, USA.
University of Washington · USWashington State University Spokane · USFred Hutch Cancer Center · USGeorgia Highlands College · USMedStar Health · USNative Health · USWashington State University · US

Funding

Contingency Management Treatment of Alcohol Abuse American Indian PeopleR01AA022070 · NIAAA · WASHINGTON STATE UNIVERSITY · PI BUCHWALD, DEDRA S, MCDONELL, MICHAEL G · 2013 to 2017
$3.5M
NIAAA NIH HHS R01 AA022070NIAAA NIH HHS R01AA022070
6 · The paper itself

Abstract

backgroundDisproportionately high rates of alcohol use disorders are present in many American Indian/Alaska Native (AI/AN) communities, yet little information exists regarding the effectiveness of alcohol treatments in AI/AN populations. Contingency management is an intervention for illicit drug use in which tangible reinforcers (rewards) are provided when patients demonstrate abstinence as assessed by urine drug tests. Contingency management has not been widely studied as an intervention for alcohol problems because until recently, no alcohol biomarker has been available to adequately verify abstinence.

aimsThe HONOR Study is designed to determine whether a culturally-tailored contingency management intervention is an effective intervention for AI/AN adults who suffer from alcohol use disorders.

methodsParticipants include 400 AI/AN alcohol-dependent adults residing in one rural reservation, one urban community, as well as a third site to be decided, in the Western U.S. Participants complete a 4-week lead-in phase prior to randomization, then 12 weeks of either a contingency management intervention for alcohol abstinence, or a control condition where participants receive reinforcers for attending study visits regardless of alcohol use. Participants are then followed for 3-more months post-intervention. The primary study outcome is urinary ethyl glucuronide-confirmed alcohol abstinence; secondary outcomes include self-reported alcohol and drug use, HIV risk behaviors, and self-reported cigarette smoking. DISCUSSION: This will be the largest randomized, controlled trial of any alcohol for AI/ANs and the largest contingency management study targeting alcohol use disorders, thus providing important information to AI/AN communities and the alcohol treatment field in general.

Indexed as

AlcoholismAmerican Indian or Alaska NativeBehavior TherapyCulturally Competent CareRewardFocus GroupsGlucuronatesHIV InfectionsHumansQualitative ResearchRisk-TakingSmokingSubstance-Related DisordersUnited Statesethyl glucuronideGlucuronatesAlaska NativesAlcoholAlcohol biomarkerAmerican IndiansContingency managementEthyl glucuronideTreatment

Identifiers

PMID26706667
PMCPMC4818164
OpenAlexW2200117851

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.