Evidence map›Paper›PMID 26706187›Full record

ArticleJournal of vascular and interventional radiology : JVIR2016

In Vitro Capture of Small Ferrous Particles with a Magnetic Filtration Device Designed for Intravascular Use with Intraarterial Chemotherapy: Proof-of-Concept Study.

Marc C Mabray, Prasheel Lillaney, Chia-Hung Sze, Aaron D Losey, Jeffrey Yang, Sravani Kondapavulur, Derek Liu, Maythem Saeed, Anand Patel, Daniel Cooke and 4 more

Abstract read
In one paragraph

Article in Journal of vascular and interventional radiology : JVIR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. 3D Printed Biosponge Adsorbers for Capturing Toxic Chemotherapy DrugsACS biomaterials science & engineering · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Quantification ofJournal of magnetic resonance imaging : JMRI · 2018
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Marc C MabrayDepartment of Radiology and Biomedical Imaging, San Francisco, California. Electronic address: marc.mabray@ucsf.edu.
Prasheel LillaneyDepartment of Radiology and Biomedical Imaging, San Francisco, California.
Chia-Hung SzeDepartment of Radiology and Biomedical Imaging, San Francisco, California.
Aaron D LoseyDepartment of Radiology and Biomedical Imaging, San Francisco, California.
Jeffrey YangDepartment of Radiology and Biomedical Imaging, San Francisco, California.
Sravani KondapavulurDepartment of Bioengineering, University of California, Berkeley, Berkeley, California.
Derek LiuDepartment of Bioengineering, University of California, Berkeley, Berkeley, California.
Maythem SaeedDepartment of Radiology and Biomedical Imaging, San Francisco, California.
Anand PatelDepartment of Radiology and Biomedical Imaging, San Francisco, California.
Daniel CookeDepartment of Radiology and Biomedical Imaging, San Francisco, California.
Young-Wook JunDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, San Francisco, California.
Ivan El-SayedDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, San Francisco, California.
Mark WilsonDepartment of Radiology and Biomedical Imaging, San Francisco, California.
Steven W HettsDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, San Francisco, California.

Funding

Biomedical Imaging for Clinician ScientistsT32EB001631 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI THOMAS M LINK · 2005 to 2026
$5.6M
Endovascular Magnetic Catheter for Interventional MRIR01EB012031 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HETTS, STEVEN WILLIAM, MARTIN, ALASTAIR J · 2011 to 2021
$4.8M
Endovascular Chemofiltration: Optimizing Removal of Chemotherapeutics and Nanoparticles from the Blood to Reduce ToxicityR01CA194533 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HETTS, STEVEN WILLIAM · 2015 to 2019
$2.6M
Immersive Team-Based Design in Undergraduate Bioengineering EducationR25EB013068 · NIBIB · UNIVERSITY OF CALIFORNIA BERKELEY · PI HERR, AMY ELIZABETH · 2011 to 2020
$379k
ChemoFilter: A Novel Catheter Device to Enable High-Dose Chemotherapy TreatmentR41CA183327 · NCI · CHEMOFILTER, INC. · PI PATEL, ANAND S · 2014 to 2014
$225k
NCI NIH HHS 1R01CA194533NCI NIH HHS 1R41CA183327NCI NIH HHS R01 CA194533NCI NIH HHS R41 CA183327NIBIB NIH HHS 5R01EB012031NIBIB NIH HHS 5T32EB001631-10NIBIB NIH HHS R01 EB012031NIBIB NIH HHS R25 EB013068NIBIB NIH HHS R25EB013068NIBIB NIH HHS T32 EB001631
6 · The paper itself

Abstract

purposeTo establish that a magnetic device designed for intravascular use can bind small iron particles in physiologic flow models. MATERIALS AND

methodsUncoated iron oxide particles 50-100 nm and 1-5 µm in size were tested in a water flow chamber over a period of 10 minutes without a magnet (ie, control) and with large and small prototype magnets. These same particles and 1-µm carboxylic acid-coated iron oxide beads were likewise tested in a serum flow chamber model without a magnet (ie, control) and with the small prototype magnet.

resultsParticles were successfully captured from solution. Particle concentrations in solution decreased in all experiments (P < .05 vs matched control runs). At 10 minutes, concentrations were 98% (50-100-nm particles in water with a large magnet), 97% (50-100-nm particles in water with a small magnet), 99% (1-5-µm particles in water with a large magnet), 99% (1-5-µm particles in water with a small magnet), 95% (50-100-nm particles in serum with a small magnet), 92% (1-5-µm particles in serum with a small magnet), and 75% (1-µm coated beads in serum with a small magnet) lower compared with matched control runs.

conclusionsThis study demonstrates the concept of magnetic capture of small iron oxide particles in physiologic flow models by using a small wire-mounted magnetic filter designed for intravascular use.

Indexed as

Drug CarriersMagnetsAntineoplastic AgentsDrug CompoundingEquipment DesignFerric CompoundsFerrous CompoundsFiltrationInjections, Intra-ArterialMaterials TestingModels, CardiovascularParticle SizeRegional Blood FlowTime FactorsAntineoplastic AgentsDrug CarriersFerric Compoundsferric oxideFerrous Compoundsferrous oxide

Identifiers

PMID26706187
PMCPMC4769113

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.