ArticleJournal of bronchology & interventional pulmonology2016
Comparison of Transbronchial and Cryobiopsies in Evaluation of Diffuse Parenchymal Lung Disease.
Article in Journal of bronchology & interventional pulmonology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Yield and safety of different biopsy types in interstitial lung disease: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026Pooled it
- Diagnostic yield and safety of transbronchial lung cryobiopsy and surgical lung biopsy in interstitial lung diseases: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2022Pooled it
- Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2022Guideline
- Diagnosis of Hypersensitivity Pneumonitis in Adults. An Official ATS/JRS/ALAT Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2020Guideline
- Cryobiopsy for diagnosing acute fibrinous and organizing pneumonia during breast cancer treatment: A case report.Experimental and therapeutic medicine · 2025Article
- The Role of Bronchoscopy in the Diagnosis of Interstitial Lung Disease: A State-of-the-Art Review.Journal of clinical medicine · 2025Review
- Sequential Development of Waldenström's Macroglobulinemia After High-Grade Lymphomatoid Granulomatosis.Cureus · 2025Article
- Use of a pulmosphere model to evaluate drug antifibrotic responses in interstitial lung diseases.Respiratory research · 2023Article
- Is conventional transbronchial lung biopsy out: The evaluation of clinical value in diffuse parenchymal lung disease.The clinical respiratory journal · 2022Article
- Single-centre experience of transbronchial cryobiopsy as a first choice method for the diagnosis of interstitial lung disease.Indian journal of thoracic and cardiovascular surgery · 2022Article
- Article
- Complications following transbronchial biopsy: the role of cryobiopsy in the incidence of postoperative pneumothoraxRevista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2021Article
- The value of virtual bronchoscopic navigation and radial endobronchial ultrasound-guided transbronchial lung cryobiopsies for pulmonary lymphangitic carcinomatosis.Journal of thoracic disease · 2020Article
- Diagnostic approach in parenchymal lung diseases: transbronchial lung biopsy or cryobiopsy?Turkish journal of medical sciences · 2020Article
- Bronchoscopic Cryobiopsy and Forceps Biopsy for the Diagnostic Evaluation of Diffuse Parenchymal Lung Disease in Clinical Practice.Mayo Clinic proceedings. Innovations, quality & outcomes · 2020Article
- Transbronchial Lung Cryobiopsy in Idiopathic Pulmonary Fibrosis: A State of the Art Review.Advances in therapy · 2019Review
- The value of using radial endobronchial ultrasound to guide transbronchial lung cryobiopsy.Journal of thoracic disease · 2019Review
- Interstitial lung disease: the diagnostic role of bronchoscopy.Journal of thoracic disease · 2017Review
- Transbronchial cryobiopsy for diffuse parenchymal lung disease: a state-of-the-art review of procedural techniques, current evidence, and future challenges.Journal of thoracic disease · 2017Review
- Article
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Abstract
backgroundDiffuse parenchymal lung diseases (DPLDs) are common. An accurate diagnosis is essential due to differences in etiology, clinicopathologic features, therapeutic options, and prognosis. Transbronchial lung biopsies (TBLBs) are often limited by small specimen size, crush artifact, and other factors. Transbronchial lung cryobiopsies (TBLCs) are under investigation to overcome these limitations.
methodsWe conducted a retrospective study of 56 patients in a single, tertiary-care academic center to compare the yield of both techniques when performed in the same patient. Patients underwent flexible bronchoscopy using moderate sedation with TBLB followed by TBLC in the most radiographically abnormal areas. Clinical data and postprocedural outcomes were reviewed, with a final diagnosis made utilizing a multidisciplinary approach.
resultsThe mean age of patients was 60 years and 54% were male. Comorbidities included COPD (14%) and prior malignancy (48%). The number of TBLB specimens ranged from 1 to 10 per patient (mean 4) and size varied from 0.1 to 0.8 cm. The number of TBLC specimens ranged from 1 to 4 per patient (mean 2) and size ranged from 0.4 to 2.6 cm. Both techniques provided the same diagnosis in 26 patients (46%). An additional 11 (20%) patients had a diagnosis established by adding TBLC to TBLB. Compared with TBLB, TBLC had a higher diagnostic yield in patients with hypersensitivity pneumonitis and interstitial lung disease. Only 2 patients required video-assisted thoracoscopic surgery to establish a diagnosis. Complications included pneumothorax (20%) and massive hemoptysis (2%).
conclusionTBLC used with TBLB can improve the diagnostic yield of flexible bronchoscopy in patients with DPLD.
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