Evidence map›Paper›PMID 26704893›Full record

SynthesisAmerican journal of obstetrics and gynecology2016

Functional status in older women diagnosed with pelvic organ prolapse.

Tatiana V D Sanses, Nicholas K Schiltz, Bruna M Couri, Sangeeta T Mahajan, Holly E Richter, David F Warner, Jack Guralnik, Siran M Koroukian

Open access · bronzeAbstract readMeta-Analysis
In one paragraph

Synthesis in American journal of obstetrics and gynecology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Tatiana V D SansesUniversity of Maryland School of Medicine, Baltimore, MD. Electronic address: tsanses@fpi.umaryland.edu.
Nicholas K SchiltzCase Western Reserve University, Cleveland, OH.
Bruna M CouriCleveland Clinic, Cleveland, OH.
Sangeeta T MahajanCase Western Reserve University, Cleveland, OH; University Hospitals Case Medical Center, Cleveland, OH.
Holly E RichterUniversity of Alabama at Birmingham School of Medicine, Birmingham, AL.
David F WarnerUniversity of Nebraska-Lincoln, Lincoln, NE.
Jack GuralnikUniversity of Maryland School of Medicine, Baltimore, MD.
Siran M KoroukianCase Western Reserve University, Cleveland, OH.
Case Western Reserve University · USUniversity of Maryland, Baltimore · USCleveland Clinic · USUniversity Hospitals of Cleveland · USUniversity of Alabama at Birmingham · USUniversity of Nebraska–Lincoln · US

Funding

Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI Stephen L. Seliger · 2006 to 2026
$28.9M
Clinical and Translational Science Collaborative of ClevelandKL2TR000440 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$11.1M
Maryland's Organized Research Effort in Women's Health (MORE-WH)K12HD043489 · NICHD · UNIVERSITY OF MARYLAND BALTIMORE · PI TRACY, J. KATHLEEN · 2002 to 2016
$7.0M
Statistical methods for vitamin D targets for functional outcomes in older adultsR01AG048069 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI SHARDELL, MICHELLE DENISE · 2015 to 2025
$4.3M
Combination of chronic conditions determining clinical relevance and resource useR21HS023113 · AHRQ · CASE WESTERN RESERVE UNIVERSITY · PI KOROUKIAN, SIRAN M. · 2014 to 2014
$179k
AHRQ HHS R21 HS023113NCATS NIH HHS KL2 TR000440NCATS NIH HHS UL1 TR000439NIA NIH HHS P30 AG028747NIA NIH HHS R01 AG048069NICHD NIH HHS K12 HD043489
6 · The paper itself

Abstract

backgroundFunctional status plays an important role in the comprehensive characterization of older adults. Functional limitations are associated with an increased risk of adverse treatment outcomes, but there are limited data on the prevalence of functional limitations in older women with pelvic floor disorders.

objectiveThe aim of the study was to describe the prevalence of functional limitations based on health status in older women with pelvic organ prolapse (POP). STUDY

designThis pooled, cross-sectional study utilized data from the linked Health and Retirement Study and Medicare files from 1992 through 2008. The analysis included 890 women age ≥65 years with POP. We assessed self-reported functional status, categorized in strength, upper and lower body mobility, activities of daily living (ADL), and instrumental ADL (IADL) domains. Functional limitations were evaluated and stratified by respondents self-reported general health status. Descriptive statistics were used to compare categorical and continuous variables, and logistic regression was used to measure differences in the odds of functional limitation by increasing age.

resultsThe prevalence of functional limitations was 76.2% in strength, 44.9% in upper and 65.8% in lower body mobility, 4.5% in ADL, and 13.6% in IADL. Limitations were more prevalent in women with poor or fair health status than in women with good health status, including 91.5% vs 69.9% in strength, 72.9% vs 33.5% in upper and 88.0% vs 56.8% in lower body mobility, 11.6% vs 0.9% in ADL, and 30.6% vs 6.7% in IADL; all P < .01. The odds of all functional limitations also increased significantly with advancing age.

conclusionFunctional limitations, especially in strength and body mobility domains, are highly prevalent in older women with POP, particularly in those with poor or fair self-reported health status. Future research is necessary to evaluate if functional status affects clinical outcomes in pelvic reconstructive and gynecologic surgery and whether it should be routinely assessed in clinical decision-making when treating older women with POP.

Indexed as

Health StatusActivities of Daily LivingAgedAged, 80 and overAgingCross-Sectional StudiesFemaleHealth SurveysHumansMedicareMiddle AgedMobility LimitationMuscle StrengthPelvic Organ ProlapseUnited StatesUpper Extremityactivities of daily livingfunctional statuslimitationsmobilitypelvic organ prolapsestrength

Identifiers

PMID26704893
PMCPMC4851569
OpenAlexW2197465938

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.