ArticleJournal of materials science. Materials in medicine2016
Hemocompatibility of styrenic block copolymers for use in prosthetic heart valves.
Article in Journal of materials science. Materials in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 27 citations in OpenAlex.
- Dynamic blood compatibility assessment of coronary stents using an innovative pneumatic blood pump to generate physiological flow rates in small sample chambers.Journal of materials science. Materials in medicine · 2025Article
- Innovation and Development in Polymer Heart Valves: A New Era of Transcatheter Aortic Valve Replacement.European cardiology · 2025Review
- Rethinking mechanical heart valves in the aortic position: new paradigms in design and testing.Frontiers in cardiovascular medicine · 2024Review
- Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response.Science advances · 2023Article
- Polymeric prosthetic heart valves: A review of current technologies and future directions.Frontiers in cardiovascular medicine · 2023Review
- Polymerisation-Induced Self-Assembly of Graft Copolymers.Angewandte Chemie (International ed. in English) · 2022Article
- Anti-thrombogenic coatings for devices in neurointerventional surgery: Case report and review of the literature.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2019Review
- A Computational Tool for the Microstructure Optimization of a Polymeric Heart Valve Prosthesis.Journal of biomechanical engineering · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Certain styrenic thermoplastic block copolymer elastomers can be processed to exhibit anisotropic mechanical properties which may be desirable for imitating biological tissues. The ex-vivo hemocompatibility of four triblock (hard-soft-hard) copolymers with polystyrene hard blocks and polyethylene, polypropylene, polyisoprene, polybutadiene or polyisobutylene soft blocks are tested using the modified Chandler loop method using fresh human blood and direct contact cell proliferation of fibroblasts upon the materials. The hemocompatibility and durability performance of a heparin coating is also evaluated. Measures of platelet and coagulation cascade activation indicate that the test materials are superior to polyester but inferior to expanded polytetrafluoroethylene and bovine pericardium reference materials. Against inflammatory measures the test materials are superior to polyester and bovine pericardium. The addition of a heparin coating results in reduced protein adsorption and ex-vivo hemocompatibility performance superior to all reference materials, in all measures. The tested styrenic thermoplastic block copolymers demonstrate adequate performance for blood contacting applications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.