ArticleJournal of the American Academy of Child and Adolescent Psychiatry2016
Developmental Timing of Trauma Exposure Relative to Puberty and the Nature of Psychopathology Among Adolescent Girls.
Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Neurobiological Alterations in Females With PTSD: A Systematic Review.Frontiers in psychiatry · 2022Pooled it
- Population-level encoding of task information is stronger in the adolescent compared to adult frontal cortex.Developmental cognitive neuroscience · 2026Article
- Adolescent Neural Reactivity to Alcohol Cues: The Role of Violence Exposure and Coping Motives.Behavioral sciences (Basel, Switzerland) · 2026Article
- Age- and sex-dependent effects of stressors on activity of the nucleus reuniens of the thalamus.Schizophrenia research · 2025Article
- Trauma and Sensory Systems: Biological Mechanisms Involving the Skin and the 17q21 Gene Cluster.Biological psychiatry · 2025Review
- The Association Between a Neighborhood Adverse Childhood Experiences Index and Body Mass Index Among New York City Youth.Childhood obesity (Print) · 2024Article
- The multiscale topological organization of the functional brain network in adolescent PTSD.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Parental and Adolescents' Anxiety during the COVID-19 Outbreak in Rural China: The role of Parent-child Communication.Journal of child & adolescent trauma · 2024Article
- Childhood adversity and psychopathology: the dimensions of timing, type and chronicity in a population-based sample of high-risk adolescents.Child and adolescent psychiatry and mental health · 2024Article
- Latent profiles of substance use, early life stress, and attention/externalizing problems and their association with neural correlates of reinforcement learning in adolescents.Psychological medicine · 2023Article
- Sex-related differences in violence exposure, neural reactivity to threat, and mental health.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
- Developmental Timing of Trauma in Women Predicts Unique Extracellular Vesicle Proteome Signatures.Biological psychiatry · 2022Article
- Role of Posterodorsal Medial Amygdala Urocortin-3 in Pubertal Timing in Female Mice.Frontiers in endocrinology · 2022Article
- Trauma during Early Adolescence and Boys' Social Behavior: A Focus on Teen Dating Violence.Journal of child & adolescent trauma · 2021Article
- Subclinical Anxiety and Posttraumatic Stress Influence Cortical Thinning During Adolescence.Journal of the American Academy of Child and Adolescent Psychiatry · 2021Article
- Lifetime risk of suicide among survivors of the atomic bombings of Japan.Epidemiology and psychiatric sciences · 2021Article
- Posttraumatic Stress Disorder and the Developing Adolescent Brain.Biological psychiatry · 2021Review
- Case Report: When Does Puberty Become Traumatic?Frontiers in psychiatry · 2021Article
- Sex-Specific Associations Between Trauma Exposure, Pubertal Timing, and Anxiety in Black Children.Frontiers in human neuroscience · 2021Article
- Genes and environments, development and time.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
objectiveIncreased neuroplasticity and neural development during puberty provide a context for which stress and trauma can have dramatic and long-lasting effects on psychological systems; therefore, this study was designed to determine whether exposure to potentially traumatic events during puberty uniquely predicts adolescent girls' psychopathology. Because neural substrates associated with different forms of psychopathology seemingly develop at different rates, the possibility that the developmental timing of trauma relative to puberty predicts the nature of psychopathology (posttraumatic stress disorder [PTSD], depressive, and anxiety disorders) was examined.
methodA subset of 2,899 adolescent girls from the National Comorbidity Survey Replication-Adolescent Supplement who completed the study 2+ years postmenarche was selected. Past-year psychiatric disorders and reports of age of trauma exposure were assessed using the Composite International Diagnostic Interview. Developmental stages were defined as the 2 years after the year of menarche ("postpuberty"), 3 years before and year of menarche ("puberty"), 2 to 6 years before the puberty period ("grade school"), and 4 to 5 years after birth ("infancy-preschool").
resultsCompared to other developmental periods, trauma during puberty conferred significantly more risk (50.47% of model R(2)) for girls' past-year anxiety disorder diagnoses (primarily social phobia), whereas trauma during the grade school period conferred significantly more risk (47.24% of model R(2)) for past-year depressive disorder diagnoses. Recency of trauma best predicted past-year PTSD diagnoses.
conclusionSupporting rodent models, puberty may be a sensitive period for the impact of trauma on girls' development of an anxiety disorder. Trauma prepuberty or postpuberty distinctly predicts depression or PTSD, suggesting differential etiological processes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.