ReviewJournal of functional biomaterials2015
Fabrication, Properties and Applications of Dense Hydroxyapatite: A Review.
Review in Journal of functional biomaterials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed.
- Fabrication of Biphasic Hydroxyapatite/Calcium Sulfate Blocks via Hydrothermal Partial Phase Transformation for Bone Substitutes.European journal of dentistry · 2026Article
- Development of a Nano-Hybrid Composite Using Bovine Hydroxyapatite and Montmorillonite for Endodontic Applications-An In Vitro Study.International endodontic journal · 2026Article
- Preliminary Formulation-Dependent Angiogenesis-Related and Early Osteogenic Responses to Three-Dimensional Bioprinted Hydroxyapatite-Acrylated Palm Olein Scaffolds: An In Vitro Study.International journal of molecular sciences · 2026Article
- Surface-Exposed Hydroxyapatite Microparticles in Electrospun PLLA Scaffolds: Mechanical Reinforcement and Osteogenic Response.Polymers · 2026Article
- Granulate-to-Filament: An Extrusion-Mixed PLA-Human Bone Material System for 3D-Printed Bone Scaffolds.Journal of functional biomaterials · 2026Article
- Applicability of Whole Blood Monocyte Activation Test for Endotoxin Activity Assessment in Hydroxyapatite-Based Ceramics.Bioengineering (Basel, Switzerland) · 2026Article
- Biofunctionalization of Stem Cell Scaffold for Osteogenesis and Bone Regeneration.Biomolecules · 2025Review
- Artificial ligaments in anterior cruciate ligament reconstruction: Coating strategies for PET-based materials.Journal of orthopaedic translation · 2025Review
- Material Extrusion of the Poly(lactic acid)/HAp Nanocomposite Scaffold for Bone Tissue Applications: A Comprehensive Investigation.ACS omega · 2025Article
- Hydroxyapatite microspheres encapsulated within hybrid hydrogel promote skin regeneration through the activation of Calcium Signaling and Motor Protein pathway.Bioactive materials · 2025Article
- Study of New Glass-Ceramic and Dense Ceramic Containing Biogenic Hydroxyapatite.Materials (Basel, Switzerland) · 2025Article
- Effect of Laser Surface Texturing and Fabrication Methods on Tribological Properties of Ti6Al4V/HAp Biocomposites.Materials (Basel, Switzerland) · 2025Article
- Manganese dioxide- and cobalt oxide-doped hydroxyapatite with curcumin for orthopedic and dental applications.Journal of materials research · 2025Article
- Synergistic impact of osseointegration and multifunctionality on functionally graded ceramic composites for bone healing applications.Scientific reports · 2025Article
- Fabrication and Characterization of Highly Porous Gyroid Scaffolds Composed of Deproteinized Bone Mineral.Journal of functional biomaterials · 2025Article
- Advances in the application and research of biomaterials in promoting bone repair and regeneration through immune modulation.Materials today. Bio · 2025Review
- Tailoring the surface pore morphology of bioceramic scaffolds through colloidal processing for bone tissue engineering.PloS one · 2025Article
- Article
- Biocompatible nanocomposite hydroxyapatite-based granules with increased specific surface area and bioresorbability for bone regenerative medicine applications.Scientific reports · 2024Article
- Role of TiScientific reports · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the last five decades, there have been vast advances in the field of biomaterials, including ceramics, glasses, glass-ceramics and metal alloys. Dense and porous ceramics have been widely used for various biomedical applications. Current applications of bioceramics include bone grafts, spinal fusion, bone repairs, bone fillers, maxillofacial reconstruction, etc. Amongst the various calcium phosphate compositions, hydroxyapatite, which has a composition similar to human bone, has attracted wide interest. Much emphasis is given to tissue engineering, both in porous and dense ceramic forms. The current review focusses on the various applications of dense hydroxyapatite and other dense biomaterials on the aspects of transparency and the mechanical and electrical behavior. Prospective future applications, established along the aforesaid applications of hydroxyapatite, appear to be promising regarding bone bonding, advanced medical treatment methods, improvement of the mechanical strength of artificial bone grafts and better in vitro/in vivo methodologies to afford more particular outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.